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Auranofin

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For Research Use Only | Not For Clinical Use
CATIAR4241895
MDL NumberMFCD00080759
Molecular Weight678.48
EC Number251-801-9
InChI KeyAUJRCFUBUPVWSZ-XTZHGVARSA-M
Description≥98% (HPLC)
SolubilityDMSO: ≥5 mg/mL
Assay≥98% (HPLC)
Formpowder
Size10MG, 50MG
Storage Conditionsroom temp
1

Auranofin Activity Exposes Thioredoxin Reductase as a Viable Drug Target in

Mike Marvin Ruth, Mara van Rossum, Valerie A C M Koeken, Lian J Pennings, Elin M Svensson, Carolien Ruesen, Edmee C Bowles, Heiman F L Wertheim, Wouter Hoefsloot, Jakko van Ingen

Antimicrob Agents Chemother. 2019 Aug 23;63(9):e00449-19.

PMID: 31262763

1

Auranofin Enhances Ibrutinib's Anticancer Activity in EGFR-Mutant Lung Adenocarcinoma

Jing Hu, Huijuan Zhang, Mengru Cao, Li Wang, Shuhong Wu, Bingliang Fang

Mol Cancer Ther. 2018 Oct;17(10):2156-2163.

PMID: 30065099

1

Auranofin Protects Intestine Against Radiation Injury by Modulating p53/p21 Pathway and Radiosensitizes Human Colon Tumor

Dhrubajyoti Nag, Payel Bhanja, Randal Riha, Giselle Sanchez-Guerrero, Bruce F Kimler, Terance T Tsue, Chris Lominska, Subhrajit Saha

Clin Cancer Res. 2019 Aug 1;25(15):4791-4807.

PMID: 30940656

1

Potential Anticancer Activity of Auranofin

Takefumi Onodera, Isao Momose, Manabu Kawada

Chem Pharm Bull (Tokyo). 2019;67(3):186-191.

PMID: 30827998

1

Repurposing of Auranofin: Thioredoxin Reductase Remains a Primary Target of the Drug

Xiaonan Zhang, Karthik Selvaraju, Amir Ata Saei, Padraig D'Arcy, Roman A Zubarev, Elias Sj Arnér, Stig Linder

Biochimie. 2019 Jul;162:46-54.

PMID: 30946948

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