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AZ12216052

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For Research Use Only | Not For Clinical Use
CATAP1290628317
CAS1290628-31-7
MDL NumberMFCD20926426
Molecular Weight392.35
InChI KeyQKUYZJOTWYRWNF-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

"Selective" Class C G Protein-Coupled Receptor Modulators Are Neutral or Biased mGlu

Shane D Hellyer, Sabine Albold, Taide Wang, Amy N Y Chen, Lauren T May, Katie Leach, Karen J Gregory

Mol Pharmacol. 2018 May;93(5):504-514.

PMID: 29514854

1

Allosteric and Orthosteric Activators of mGluR8 Differentially Affect the Chemotherapeutic-Induced Human Neuroblastoma SH-SY5Y Cell Damage: The Impact of Cell Differentiation State

Danuta Jantas, Beata Grygier, Justyna Zatorska, Władysław Lasoń

Basic Clin Pharmacol Toxicol. 2018 Oct;123(4):443-451.

PMID: 29753314

1

Neuroprotective Effects of Metabotropic Glutamate Receptor Group II and III Activators Against MPP(+)-induced Cell Death in Human Neuroblastoma SH-SY5Y Cells: The Impact of Cell Differentiation State

D Jantas, A Greda, S Golda, M Korostynski, B Grygier, A Roman, A Pilc, W Lason

Neuropharmacology. 2014 Aug;83:36-53.

PMID: 24713472

1

Neuroprotective Effects of mGluR II and III Activators Against Staurosporine- And Doxorubicin-Induced Cellular Injury in SH-SY5Y Cells: New Evidence for a Mechanism Involving Inhibition of AIF Translocation

D Jantas, A Greda, M Leskiewicz, B Grygier, A Pilc, W Lason

Neurochem Int. 2015 Sep;88:124-37.

PMID: 25661514

1

Opposing Roles of mGluR8 in Measures of Anxiety Involving Non-Social and Social Challenges

Robert M Duvoisin, Laura Villasana, Matthew J Davis, Danny G Winder, Jacob Raber

Behav Brain Res. 2011 Aug 1;221(1):50-4.

PMID: 21382421

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