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AZ191

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For Research Use Only | Not For Clinical Use
CATAP1594092371
CAS1594092-37-1
MDL NumberMFCD28015098
Molecular Weight429.52
InChI KeyZYVXTMKTGDARKR-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Color, white to yellow to light brown
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

[Expression and Clinical Significance of Dyrk1b in the Specimens and Cells of Cervical Lesions]

Jiao Lin, Pengxin Zhang, Lu Pang, Jingying Chen, Wen Sun, Wenjing Qi, Yunyi Lyu, Hongwei Guan, Jingchun Gao

Zhonghua Fu Chan Ke Za Zhi. 2016 Jan;51(1):40-5.

PMID: 26899006

1

A Novel DYRK1B Inhibitor AZ191 Demonstrates That DYRK1B Acts Independently of GSK3β to Phosphorylate Cyclin D1 at Thr(286), Not Thr(288)

Anne L Ashford, David Oxley, Jason Kettle, Kevin Hudson, Sylvie Guichard, Simon J Cook, Pamela A Lochhead

Biochem J. 2014 Jan 1;457(1):43-56.

PMID: 24134204

1

Encorafenib (LGX818), a Potent BRAF Inhibitor, Induces Senescence Accompanied by Autophagy in BRAFV600E Melanoma Cells

Zhen Li, Ke Jiang, Xiaofang Zhu, Guibin Lin, Fei Song, Yongfu Zhao, Yongjun Piao, Jiwei Liu, Wei Cheng, Xiaolin Bi, Peng Gong, Zhiqi Song, Songshu Meng

Cancer Lett. 2016 Jan 28;370(2):332-44.

PMID: 26586345

1

Mebendazole-induced M1 Polarisation of THP-1 Macrophages May Involve DYRK1B Inhibition

Kristin Blom, Jenny Rubin, Malin Berglund, Malin Jarvius, Lena Lenhammar, Vendela Parrow, Claes Andersson, Angelica Loskog, Mårten Fryknäs, Peter Nygren, Rolf Larsson

BMC Res Notes. 2019 Apr 22;12(1):234.

PMID: 31010428

1

Targeting DYRK1B Suppresses the Proliferation and Migration of Liposarcoma Cells

Hua Chen, Jacson Shen, Edwin Choy, Francis J Hornicek, Aijun Shan, Zhenfeng Duan

Oncotarget. 2017 Nov 28;9(17):13154-13166.

PMID: 29568347

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