0

AZ628

INQUIRY Add to cart
For Research Use Only | Not For Clinical Use
CATAP878739061
CAS878739-06-1
Structure
Molecular Weight451.52
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Pan-RAF and MEK Vertical Inhibition Enhances Therapeutic Response in non-V600 BRAF Mutant Cells

Eszter Molnár, Dominika Rittler, Marcell Baranyi, Michael Grusch, Walter Berger, Balázs Döme, József Tóvári, Clemens Aigner, József Tímár, Tamás Garay, Balázs Hegedűs

BMC Cancer. 2018 May 8;18(1):542.

PMID: 29739364

1

Resistance Mechanism of the Oncogenic β3-αC Deletion Mutation in BRAF Kinase to Dabrafenib and Vemurafenib Revealed by Molecular Dynamics Simulations and Binding Free Energy Calculations

Yuzhen Niu, Yan Zhang, Xiaojun Yao

Chem Biol Drug Des. 2019 Feb;93(2):177-187.

PMID: 30225883

1

STAT3 Inhibitor Sensitized KRAS-mutant Lung Cancers to RAF Inhibitor by Activating MEK/ERK Signaling Pathway

Zhenlin Wang, Mengchen Yin, Peilin Chu, Meiqing Lou

Aging (Albany NY). 2019 Sep 4;11(17):7187-7196.

PMID: 31484165

1

Type II RAF Inhibitor Causes Superior ERK Pathway Suppression Compared to Type I RAF Inhibitor in Cells Expressing Different BRAF Mutant Types Recurrently Found in Lung Cancer

Amir Noeparast, Philippe Giron, Sylvia De Brakeleer, Carolien Eggermont, Ulrike De Ridder, Erik Teugels, Jacques De Grève

Oncotarget. 2018 Feb 27;9(22):16110-16123.

PMID: 29662630

1

α-Ketoglutaric Acid-Modified Carbonate Apatite Enhances Cellular Uptake and Cytotoxicity of a Raf- Kinase Inhibitor in Breast Cancer Cells Through Inhibition of MAPK and PI-3 Kinase Pathways

Sultana Mehbuba Hossain, Jayalaxmi Shetty, Kyi Kyi Tha, Ezharul Hoque Chowdhury

Biomedicines. 2019 Jan 3;7(1):4.

PMID: 30609867

  • Verification code
Contact Us

Send Us a Request

What is your specific need? We will do everything we can to meet your expectations.
Online Inquiry

Inquiry

For any inquiry, question or recommendation, please call: or fill out the following form.

  • Verification code

Head Office

  • Tel:
  • Email:

Follow us on

qrcode