CAS 327056-26-8 AZD9272 - Analytical Products / Alfa Chemistry

CAT	AP327056268
CAS	327056-26-8
Structure
MDL Number	MFCD26394953
Molecular Weight	284.22

Description	≥98% (HPLC)
Solubility	DMSO: 5 mg/mL, clear (warmed)
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	room temp

1

AZD9272 and AZD2066: Selective and Highly Central Nervous System Penetrant mGluR5 Antagonists Characterized by Their Discriminative Effects

Michael D B Swedberg, Patrick Raboisson

J Pharmacol Exp Ther. 2014 Aug;350(2):212-22.

PMID: 24876235

1

Evaluation of the Effects of a Metabotropic Glutamate Receptor 5-antagonist on Electrically Induced Pain and Central Sensitization in Healthy Human Volunteers

J Kalliomäki, K Huizar, M Kågedal, B Hägglöf, M Schmelz

Eur J Pain. 2013 Nov;17(10):1465-71.

PMID: 23650072

1

Non-linear Mixed Effects Modelling of Positron Emission Tomography Data for Simultaneous Estimation of Radioligand Kinetics and Occupancy in Healthy Volunteers

Matts Kågedal, Zsolt Cselényi, Svante Nyberg, Siv Jönsson, Patrick Raboisson, Per Stenkrona, Andrew C Hooker, Mats O Karlsson

Neuroimage. 2012 Jul 16;61(4):849-56.

PMID: 22425672

1

Palladium Mediated ¹¹C-cyanation and Characterization in the Non-Human Primate Brain of the Novel mGluR5 Radioligand [¹¹C]AZD9272

Jan D Andersson, Nicholas Seneca, Phong Truong, David Wensbo, Patrick Raboisson, Lars Farde, Christer Halldin

Nucl Med Biol. 2013 May;40(4):547-53.

PMID: 23541825

1

The metabotropic glutamate receptor 5 radioligand [ 11 C]AZD9272 identifies unique binding sites in primate brain

Katarina Varnäs, Anders Juréus, Sjoerd J Finnema, Peter Johnström, Patrick Raboisson, Nahid Amini, Akihiro Takano, Vladimir Stepanov, Christer Halldin, Lars Farde

Neuropharmacology. 2018 Jun;135:455-463.

PMID: 29608920

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