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BAY 60-2770

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For Research Use Only | Not For Clinical Use
CATAP1027642438
CAS1027642-43-8
Molecular Weight623.63
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

BAY 60-2770 Activates Two Isoforms of Nitric Oxide Sensitive Guanylyl Cyclase: Evidence for Stable Insertion of Activator Drugs

Anne Sömmer, Peter Sandner, Sönke Behrends

Biochem Pharmacol. 2018 Jan;147:10-20.

PMID: 29155144

1

Soluble Guanylate Cyclase Modulators, BAY 41-2272 and BAY 60-2770, Inhibit Human and Rabbit Prostate Contractility

Fabiano B Calmasini, Eduardo C Alexandre, Fabio Henrique Silva, Gilberto De Nucci, Edson Antunes, Carlos A D'Ancona, Fabíola Z Mónica

Urology. 2016 Aug;94:312.e9-312.e15.

PMID: 27131967

1

The sGC Activator BAY 60-2770 Has Potent Erectile Activity in the Rat

George F Lasker, Edward A Pankey, Terrence J Frink, Jonathan R Zeitzer, Korey A Walter, Philip J Kadowitz

Am J Physiol Heart Circ Physiol. 2013 Jun 15;304(12):H1670-9.

PMID: 23585129

1

The Soluble Guanylyl Cyclase Activator BAY 60-2770 Ameliorates Overactive Bladder in Obese Mice

Luiz O Leiria, Fabio H Silva, Ana Paula C Davel, Eduardo C Alexandre, Marina C Calixto, Gilberto De Nucci, Fabíola Z Mónica, Edson Antunes

J Urol. 2014 Feb;191(2):539-47.

PMID: 24050894

1

The Soluble Guanylyl Cyclase Activator BAY 60-2770 Inhibits Murine Allergic Airways Inflammation and Human Eosinophil Chemotaxis

Lineu Baldissera Jr, Dalize M Squebola-Cola, Marina C Calixto, Ana P Lima-Barbosa, André L Rennó, Gabriel F Anhê, Antonio Condino-Neto, Gilberto De Nucci, Edson Antunes

Pulm Pharmacol Ther. 2016 Dec;41:86-95.

PMID: 27816773

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