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BCI-121

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For Research Use Only | Not For Clinical Use
CATAP432529823
CAS432529-82-3
Molecular Weight340.22
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth

Alessia Peserico, Aldo Germani, Paola Sanese, Armenio Jorge Barbosa, Valeria Di Virgilio, Raffaella Fittipaldi, Edoardo Fabini, Carlo Bertucci, Greta Varchi, Mary Pat Moyer, Giuseppina Caretti, Alberto Del Rio, etc.

J Cell Physiol. 2015 Oct;230(10):2447-2460.

PMID: 25728514

1

Amplification of SMYD3 Promotes Tumorigenicity and Intrahepatic Metastasis of Hepatocellular Carcinoma via Upregulation of CDK2 and MMP2

Yu Wang, Bin-Hui Xie, Wei-Hao Lin, Yong-Hui Huang, Jia-Yan Ni, Jie Hu, Wei Cui, Jun Zhou, Long Shen, Lin-Feng Xu, Fan Lian, He-Ping Li

Oncogene. 2019 Jun;38(25):4948-4961.

PMID: 30842588

1

Overexpression of SMYD3 in Ovarian Cancer Is Associated With Ovarian Cancer Proliferation and Apoptosis via Methylating H3K4 and H4K20

Yahui Jiang, Tianjiao Lyu, Xiaoxia Che, Nan Jia, Qin Li, Weiwei Feng

J Cancer. 2019 Jul 8;10(17):4072-4084.

PMID: 31417652

1

SET and MYND Domain Containing Protein 3 in Cancer

Lei Huang, A-Man Xu

Am J Transl Res. 2017 Jan 15;9(1):1-14.

PMID: 28123630

1

SMYD3 Promotes Implant Metastasis of Ovarian Cancer via H3K4 Trimethylation of Integrin Promoters

Tianjiao Lyu, Yahui Jiang, Nan Jia, Xiaoxia Che, Qin Li, Yinhua Yu, Keqin Hua, Robert C Bast Jr, Weiwei Feng

Int J Cancer. 2020 Mar 15;146(6):1553-1567.

PMID: 31503345

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