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BCMA human

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For Research Use Only | Not For Clinical Use
CATIAR4248878
Descriptionrecombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Assay≥98% (HPLC); ≥98% (SDS-PAGE)
Formlyophilized
Impurity Content<0.1 EU/μg endotoxin, tested
Size20μG
Storage Conditions−20°C
1

APRIL and BCMA Promote Human Multiple Myeloma Growth and Immunosuppression in the Bone Marrow Microenvironment

Yu-Tzu Tai, Chirag Acharya, Gang An, Michele Moschetta, Mike Y Zhong, Xiaoyan Feng, Michele Cea, Antonia Cagnetta, Kenneth Wen, Hans van Eenennaam, Andrea van Elsas, Lugui Qiu, Paul Richardson, Nikhil Munshi, etc.

Blood. 2016 Jun 23;127(25):3225-36.

PMID: 27127303

1

B Cell Maturation Antigen-Specific CAR T Cells Are Clinically Active in Multiple Myeloma

Adam D Cohen, Alfred L Garfall, Edward A Stadtmauer, J Joseph Melenhorst, Simon F Lacey, Eric Lancaster, Dan T Vogl, Brendan M Weiss, Karen Dengel, Annemarie Nelson, Gabriela Plesa, Fang Chen, Megan M Davis, etc.

J Clin Invest. 2019 Mar 21;129(6):2210-2221.

PMID: 30896447

1

B-cell Maturation Antigen Is a Promising Target for Adoptive T-cell Therapy of Multiple Myeloma

Robert O Carpenter, Moses O Evbuomwan, Stefania Pittaluga, Jeremy J Rose, Mark Raffeld, Shicheng Yang, Ronald E Gress, Frances T Hakim, James N Kochenderfer

Clin Cancer Res. 2013 Apr 15;19(8):2048-60.

PMID: 23344265

1

CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth

Robert Berahovich, Hua Zhou, Shirley Xu, Yuehua Wei, Jasper Guan, Jian Guan, Hizkia Harto, Shuxiang Fu, Kaihuai Yang, Shuying Zhu, Le Li, Lijun Wu, Vita Golubovskaya

Cancers (Basel). 2018 Sep 11;10(9):323.

PMID: 30208593

1

Development and Evaluation of an Optimal Human Single-Chain Variable Fragment-Derived BCMA-Targeted CAR T Cell Vector

Eric L Smith, Mette Staehr, Reed Masakayan, Ishan J Tatake, Terence J Purdon, Xiuyan Wang, Pei Wang, Hong Liu, Yiyang Xu, Sarah C Garrett-Thomson, Steven C Almo, Isabelle Riviere, Cheng Liu, Renier J Brentjens

Mol Ther. 2018 Jun 6;26(6):1447-1456.

PMID: 29678657

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