CAS 778270-11-4 Bcr-abl Inhibitor - CAS 778270-11-4 - Analytical Products / Alfa Chemistry

Description	The Bcr-abl Inhibitor, also referenced under CAS 778270-11-4, controls the biological activity of Bcr-abl. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Solubility	DMSO: 10 mg/mL; ethanol: 2 mg/mL
Assay	≥97% (HPLC)
Color	white
Form	solid; protect from light
Size	5MG
Storage Conditions	+2C to +8C

1

Action of the Src Family Kinase Inhibitor, Dasatinib (BMS-354825), on Human Prostate Cancer Cells

Sangkil Nam, Donghwa Kim, Jin Q Cheng, Shumin Zhang, Ji-Hyun Lee, Ralf Buettner, Janni Mirosevich, Francis Y Lee, Richard Jove

Cancer Res. 2005 Oct 15;65(20):9185-9.

PMID: 16230377

1

Effect of a Selective Abl Tyrosine Kinase Inhibitor, STI571, on in Vitro Growth of BCR-ABL-positive Acute Lymphoblastic Leukemia Cells

Y Kawaguchi, I Jinnai, K Nagai, F Yagasaki, Y Yakata, T Matsuo, K Kuriyama, M Tomonaga

Leukemia. 2001 Apr;15(4):590-4.

PMID: 11368361

1

Inhibition of Src Family Kinases With Dasatinib Blocks Migration and Invasion of Human Melanoma Cells

Ralf Buettner, Tania Mesa, Adina Vultur, Frank Lee, Richard Jove

Mol Cancer Res. 2008 Nov;6(11):1766-74.

PMID: 19010823

1

Paxillin Interactions

C E Turner

J Cell Sci. 2000 Dec;113 Pt 23:4139-40.

PMID: 11069756

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