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BG45

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For Research Use Only | Not For Clinical Use
CATAP926259996
CAS926259-99-6
Molecular Weight214.22
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Design, Synthesis and Biological Screening of 2-aminobenzamides as Selective HDAC3 Inhibitors With Promising Anticancer Effects

Prakruti Trivedi, Nilanjan Adhikari, Sk Abdul Amin, Tarun Jha, Balaram Ghosh

Eur J Pharm Sci. 2018 Nov 1;124:165-181.

PMID: 30171982

1

HDAC3 Regulates DNMT1 Expression in Multiple Myeloma: Therapeutic Implications

T Harada, H Ohguchi, Y Grondin, S Kikuchi, M Sagawa, Y-T Tai, R Mazitschek, T Hideshima, K C Anderson

Leukemia. 2017 Dec;31(12):2670-2677.

PMID: 28490812

1

Histone Deacetylase 3 as a Novel Therapeutic Target in Multiple Myeloma

J Minami, R Suzuki, R Mazitschek, G Gorgun, B Ghosh, D Cirstea, Y Hu, N Mimura, H Ohguchi, F Cottini, J Jakubikova, N C Munshi, S J Haggarty, P G Richardson, T Hideshima, K C Anderson

Leukemia. 2014 Mar;28(3):680-9.

PMID: 23913134

1

Histone Deacetylase Inhibitor BG45-mediated HO-1 Expression Induces Apoptosis of Multiple Myeloma Cells by the JAK2/STAT3 Pathway

Sishi Tang, Bingqing Cheng, Nana Zhe, Dan Ma, Jibing Xu, Xinyao Li, Yongling Guo, Weibing Wu, Jishi Wang

Anticancer Drugs. 2018 Jan;29(1):61-74.

PMID: 29049036

1

Metformin Facilitates BG45‑induced Apoptosis via an anti‑Warburg Effect in Cholangiocarcinoma Cells

Dehua Tang, Lei Xu, Mingming Zhang, Robert Gregory Dorfman, Yida Pan, Qian Zhou, Lixing Zhou, Yuming Wang, Yang Li, Yuyao Yin, Lei Wang, Xiaoping Zou

Oncol Rep. 2018 Apr;39(4):1957-1965.

PMID: 29484415

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