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Bis-Imidazole phenol IDH1 inhibitor

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For Research Use Only | Not For Clinical Use
CATAP1648909732
CAS1648909-73-2
Molecular Weight366.50
InChI KeyPCIJWPBOCDNTJF-UHFFFAOYSA-N
Description≥98% (HPLC), solubility: 30 mg/mL in DMSOclear
SolubilityDMSO: 30 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Gejing Deng, Junqing Shen, Ming Yin, Jessica McManus, Magali Mathieu, Patricia Gee, Timothy He, Chaomei Shi, Olivier Bedel, Larry R McLean, Frank Le-Strat, Ying Zhang, Jean-Pierre Marquette, Qiang Gao, etc.

J Biol Chem. 2015 Jan 9;290(2):762-74.

PMID: 25391653

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