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BIX02189

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For Research Use Only | Not For Clinical Use
CATAP1265916413
CAS1265916-41-3
MDL NumberMFCD18074528
Molecular Weight440.54
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

BIX02189 Inhibits TGF-β1-induced Lung Cancer Cell Metastasis by Directly Targeting TGF-β Type I Receptor

Seong Ji Park, Yu Sun Choi, Seungkoo Lee, Young Jae Lee, Suntaek Hong, Sanghwa Han, Byung-Chul Kim

Cancer Lett. 2016 Oct 28;381(2):314-22.

PMID: 27543359

1

C1q-TNF-Related Protein-9 Promotes Cardiac Hypertrophy and Failure

Mahesh Appari, Astrid Breitbart, Florian Brandes, Malgorzata Szaroszyk, Natali Froese, Mortimer Korf-Klingebiel, Mona Malek Mohammadi, Andrea Grund, Gesine M Scharf, Honghui Wang, Carolin Zwadlo, Daniela Fraccarollo, etc.

Circ Res. 2017 Jan 6;120(1):66-77.

PMID: 27821723

1

Cardiac Fibroblast Transcriptome Analyses Support a Role for Interferogenic, Profibrotic, and Inflammatory Genes in anti-SSA/Ro-associated Congenital Heart Block

Robert M Clancy, Androo J Markham, Tanisha Jackson, Sara E Rasmussen, Miroslav Blumenberg, Jill P Buyon

Am J Physiol Heart Circ Physiol. 2017 Sep 1;313(3):H631-H640.

PMID: 28626076

1

ERK5 Plays an Essential Role in Gestational Beta-Cell Proliferation

Congde Chen, Suichun Wu, Xiaokun Lin, Dazhou Wu, Shane Fischbach, Xiangwei Xiao

Cell Prolif. 2018 Jun;51(3):e12410.

PMID: 29159830

1

Tumor Cells With KRAS or BRAF Mutations or ERK5/MAPK7 Amplification Are Not Addicted to ERK5 Activity for Cell Proliferation

Pamela A Lochhead, Jonathan Clark, Lan-Zhen Wang, Lesley Gilmour, Matthew Squires, Rebecca Gilley, Caroline Foxton, David R Newell, Stephen R Wedge, Simon J Cook

Cell Cycle. 2016;15(4):506-18.

PMID: 26959608

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