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BMS-345541

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For Research Use Only | Not For Clinical Use
CATAP547757233
CAS547757-23-3
MDL NumberMFCD07784499
Molecular Weight291.78
InChI KeyMIDKPVLYXNLFGZ-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 18 mg/mL; H2O: insoluble
Assay≥98% (HPLC)
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Activity of the Selective IκB Kinase Inhibitor BMS-345541 Against T-cell Acute Lymphoblastic Leukemia: Involvement of FOXO3a

Francesca Buontempo, Francesca Chiarini, Daniela Bressanin, Giovanna Tabellini, Fraia Melchionda, Andrea Pession, Milena Fini, Luca M Neri, James A McCubrey, Alberto M Martelli

Cell Cycle. 2012 Jul 1;11(13):2467-75.

PMID: 22713244

1

BMS-345541 Sensitizes MCF-7 Breast Cancer Cells to Ionizing Radiation by Selective Inhibition of Homologous Recombinational Repair of DNA Double-Strand Breaks

Lixian Wu, Lijian Shao, Manna Li, Junying Zheng, Junru Wang, Wei Feng, Jianhui Chang, Yan Wang, Martin Hauer-Jensen, Daohong Zhou

Radiat Res. 2013 Feb;179(2):160-70.

PMID: 23259762

1

BMS-345541 Targets Inhibitor of kappaB Kinase and Induces Apoptosis in Melanoma: Involvement of Nuclear Factor kappaB and Mitochondria Pathways

Jinming Yang, Katayoun I Amiri, James R Burke, Johannes A Schmid, Ann Richmond

Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):950-60.

PMID: 16467110

1

IKK Inhibition by BMS-345541 Suppresses Breast Tumorigenesis and Metastases by Targeting GD2+ Cancer Stem Cells

Venkata Lokesh Battula, Khoa Nguyen, Jeff Sun, Mary Kathryn Pitner, Bin Yuan, Chandra Bartholomeusz, Numsen Hail, Michael Andreeff

Oncotarget. 2017 Jun 6;8(23):36936-36949.

PMID: 28415808

1

Two Specific Drugs, BMS-345541 and Purvalanol A Induce Apoptosis of HTLV-1 Infected Cells Through Inhibition of the NF-kappaB and Cell Cycle Pathways

Emmanuel Agbottah, Wen-I Yeh, Reem Berro, Zachary Klase, Caitlin Pedati, Kyleen Kehn-Hall, Weilin Wu, Fatah Kashanchi

AIDS Res Ther. 2008 Jun 10;5:12.

PMID: 18544167

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