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BMS-536924

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For Research Use Only | Not For Clinical Use
CATAP468740434
CAS468740-43-4
MDL NumberMFCD20278190
Molecular Weight479.96
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

BMS-536924 Reverses IGF-IR-induced Transformation of Mammary Epithelial Cells and Causes Growth Inhibition and Polarization of MCF7 Cells

Beate C Litzenburger, Hyun-Jung Kim, Isere Kuiatse, Joan M Carboni, Ricardo M Attar, Marco M Gottardis, Craig R Fairchild, Adrian V Lee

Clin Cancer Res. 2009 Jan 1;15(1):226-37.

PMID: 19118050

1

BMS-536924 Sensitizes Human Epithelial Ovarian Cancer Cells to the PARP Inhibitor, 3-aminobenzamide

Marie-Claude Beauchamp, Ariane Knafo, Amber Yasmeen, Joan M Carboni, Marco M Gottardis, Michael N Pollak, Walter H Gotlieb

Gynecol Oncol. 2009 Nov;115(2):193-8.

PMID: 19699512

1

BMS-536924, an ATP-competitive IGF-1R/IR Inhibitor, Decreases Viability and Migration of Temozolomide-Resistant Glioma Cells in Vitro and Suppresses Tumor Growth in Vivo

Qiao Zhou

Onco Targets Ther. 2015 Apr 2;8:689-97.

PMID: 25897243

1

HER Receptor Signaling Confers Resistance to the Insulin-Like Growth factor-I Receptor Inhibitor, BMS-536924

Paul Haluska, Joan M Carboni, Cynthia TenEyck, Ricardo M Attar, Xiaonan Hou, Chunrong Yu, Malvika Sagar, Tai W Wong, Marco M Gottardis, Charles Erlichman

Mol Cancer Ther. 2008 Sep;7(9):2589-98.

PMID: 18765823

1

IGF1/insulin Receptor Kinase Inhibition by BMS-536924 Is Better Tolerated Than Alloxan-Induced Hypoinsulinemia and More Effective Than Metformin in the Treatment of Experimental Insulin-Responsive Breast Cancer

Carly Jade Dool, Haider Mashhedi, Mahvash Zakikhani, Stéphanie David, Yunhua Zhao, Elena Birman, Joan M Carboni, Marco Gottardis, Marie-José Blouin, Michael Pollak

Endocr Relat Cancer. 2011 Nov 14;18(6):699-709.

PMID: 21946410

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