CAS 1001350-96-4 BMS-754807 - Analytical Products / Alfa Chemistry

CAT	AP1001350964
CAS	1001350-96-4
MDL Number	MFCD18633202
Molecular Weight	461.49
InChI Key	LQVXSNNAFNGRAH-QHCPKHFHSA-N

Description	≥98% (HPLC)
Solubility	DMSO: 20 mg/mL, clear
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	room temp

1

BMS-754807 Is Cytotoxic to Non-Small Cell Lung Cancer Cells and Enhances the Effects of Platinum Chemotherapeutics in the Human Lung Cancer Cell Line A549

S Elizabeth Franks, Robert A Jones, Ritesh Briah, Payton Murray, Roger A Moorehead

BMC Res Notes. 2016 Mar 1;9:134.

PMID: 26928578

1

BMS-754807, a Small Molecule Inhibitor of Insulin-Like Growth factor-1R/IR

Joan M Carboni, Mark Wittman, Zheng Yang, Francis Lee, Ann Greer, Warren Hurlburt, Stephen Hillerman, Carolyn Cao, Glenn H Cantor, Janet Dell-John, Cliff Chen, Lorell Discenza, Krista Menard, Aixin Li, etc.

Mol Cancer Ther. 2009 Dec;8(12):3341-9.

PMID: 19996272

1

BMS-754807, a Small-Molecule Inhibitor of Insulin-Like Growth factor-1 receptor/insulin Receptor, Enhances Gemcitabine Response in Pancreatic Cancer

Niranjan Awasthi, Changhua Zhang, Winston Ruan, Margaret A Schwarz, Roderich E Schwarz

Mol Cancer Ther. 2012 Dec;11(12):2644-53.

PMID: 23047891

1

Inhibition of IGF1R Enhances 2-deoxyglucose in the Treatment of Non-Small Cell Lung Cancer

Fakeng Liu, Yuan Liu, Xiuju Liu, Kaisheng Mao, Diansheng Zhong, Adam I Marcus, Fadlo R Khuri, Shi-Yong Sun, Yulong He, Wei Zhou

Lung Cancer. 2018 Sep;123:36-43.

PMID: 30089593

1

Synthesis and in Vitro Evaluation of [18F]BMS-754807: A Potential PET Ligand for IGF-1R

Vattoly J Majo, Victoria Arango, Norman R Simpson, Jaya Prabhakaran, Suham A Kassir, Mark D Underwood, Mihran Bakalian, Peter Canoll, J John Mann, J S Dileep Kumar

Bioorg Med Chem Lett. 2013 Jul 15;23(14):4191-4.

PMID: 23743281

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