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BPTES

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For Research Use Only | Not For Clinical Use
CATAP314045391
CAS314045-39-1
Structure
MDL NumberMFCD01079848
Molecular Weight524.68
InChI KeyMDJIPXYRSZHCFS-UHFFFAOYSA-N
Description≥95% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥95% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Characterization of the Interactions of Potent Allosteric Inhibitors With Glutaminase C, a Key Enzyme in Cancer Cell Glutamine Metabolism

Qingqiu Huang, Clint Stalnecker, Chengliang Zhang, Lee A McDermott, Prema Iyer, Jason O'Neill, Shawn Reimer, Richard A Cerione, William P Katt

J Biol Chem. 2018 Mar 9;293(10):3535-3545.

PMID: 29317493

1

Combination Therapy With BPTES Nanoparticles and Metformin Targets the Metabolic Heterogeneity of Pancreatic Cancer

Amira Elgogary, Qingguo Xu, Brad Poore, Jesse Alt, Sarah C Zimmermann, Liang Zhao, Jie Fu, Baiwei Chen, Shiyu Xia, Yanfei Liu, Marc Neisser, Christopher Nguyen, Ramon Lee, Joshua K Park, Juvenal Reyes, etc.

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5328-36.

PMID: 27559084

1

Glutaminase 1 Inhibition Reduces Glycolysis and Ameliorates Lupus-like Disease in MRL/lpr Mice and Experimental Autoimmune Encephalomyelitis

Michihito Kono, Nobuya Yoshida, Kayaho Maeda, Abel Suárez-Fueyo, Vasileios C Kyttaris, George C Tsokos

Arthritis Rheumatol. 2019 Nov;71(11):1869-1878.

PMID: 31233276

1

Recent Development of Small Molecule Glutaminase Inhibitors

Minsoo Song, Soong-Hyun Kim, Chun Young Im, Hee-Jong Hwang

Curr Top Med Chem. 2018;18(6):432-443.

PMID: 29793408

1

SIRT5 Regulation of Ammonia-Induced Autophagy and Mitophagy

Lucia Polletta, Enza Vernucci, Ilaria Carnevale, Tania Arcangeli, Dante Rotili, Silvia Palmerio, Clemens Steegborn, Theresa Nowak, Mike Schutkowski, Laura Pellegrini, Luigi Sansone, Lidia Villanova, Alessandra Runci, etc.

Autophagy. 2015;11(2):253-70.

PMID: 25700560

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