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BRD4770

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For Research Use Only | Not For Clinical Use
CATAP1374601407
CAS1374601-40-7
MDL NumberMFCD23143627
Molecular Weight413.47
InChI KeyUCGWYCMPZXDHNR-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma

Yuan Yuan, Qiu Wang, Joshiawa Paulk, Stefan Kubicek, Melissa M Kemp, Drew J Adams, Alykhan F Shamji, Bridget K Wagner, Stuart L Schreiber

ACS Chem Biol. 2012 Jul 20;7(7):1152-7.

PMID: 22536950

1

Arsenic Silences Hepatic PDK4 Expression Through Activation of Histone H3K9 Methylatransferase G9a

Xi Zhang, Jianguo Wu, Jonathan Choiniere, Zhihong Yang, Yi Huang, Jason Bennett, Li Wang

Toxicol Appl Pharmacol. 2016 Aug 1;304:42-7.

PMID: 27217333

1

Combined Targeting of G9a and Checkpoint Kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse

Guillermo Urrutia, Ann Salmonson, Jorge Toro-Zapata, Thiago M de Assuncao, Angela Mathison, Nelson Dusetti, Juan Iovanna, Raul Urrutia, Gwen Lomberk

Mol Cancer Res. 2020 Mar;18(3):448-462.

PMID: 31822519

1

Gossypol and an HMT G9a Inhibitor Act in Synergy to Induce Cell Death in Pancreatic Cancer Cells

Y Yuan, A J Tang, A B Castoreno, S-Y Kuo, Q Wang, P Kuballa, R Xavier, A F Shamji, S L Schreiber, B K Wagner

Cell Death Dis. 2013 Jun 27;4(6):e690.

PMID: 23807219

1

Modulation of the Fanconi Anemia Pathway

David A Vierra, Jada L Garzon, Meghan A Rego, Morganne M Adroved, Maurizio Mauro, Niall G Howlett

Oncotarget. 2017 Jul 22;8(44):76443-76457.

PMID: 29100324

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