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Brusatol

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For Research Use Only | Not For Clinical Use
CATAP14907983
CAS14907-98-3
Structure
MDL NumberMFCD23726642
Molecular Weight520.53
Description≥95% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥95% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Brusatol Enhances the Efficacy of Chemotherapy by Inhibiting the Nrf2-mediated Defense Mechanism

Dongmei Ren, Nicole F Villeneuve, Tao Jiang, Tongde Wu, Alexandria Lau, Henry A Toppin, Donna D Zhang

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1433-8.

PMID: 21205897

1

Brusatol, an NRF2 Inhibitor for Future Cancer Therapeutic

Sabrina J Cai, Yang Liu, Sue Han, Chunzhang Yang

Cell Biosci. 2019 Jun 6;9:45.

PMID: 31183074

1

Brusatol-Mediated Inhibition of c-Myc Increases HIF-1α Degradation and Causes Cell Death in Colorectal Cancer Under Hypoxia

Eun-Taex Oh, Chan Woo Kim, Ha Gyeong Kim, Jae-Seon Lee, Heon Joo Park

Theranostics. 2017 Aug 11;7(14):3415-3431.

PMID: 28912885

1

The Protein Synthesis Inhibitor Brusatol Normalizes High-Fat Diet-Induced Glucose Intolerance in Male C57BL/6 Mice: Role of Translation Factor eIF5A Hypusination

Kyril Turpaev, Camilla Krizhanovskii, Xuan Wang, Ernest Sargsyan, Peter Bergsten, Nils Welsh

FASEB J. 2019 Mar;33(3):3510-3522.

PMID: 30462531

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