BTK active human - Analytical Products / Alfa Chemistry

CAT

IAR42411943

Description	recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)
Assay	≥80% (SDS-PAGE)
Form	aqueous solution
Size	10μG
Storage Conditions	−70°C

1

A Phase 1 Trial of Ibrutinib Plus Palbociclib in Previously Treated Mantle Cell Lymphoma

Peter Martin, Nancy L Bartlett, Kristie A Blum, Steven Park, Kami Maddocks, Jia Ruan, LeAnn Ridling, Christopher Dittus, Zhengming Chen, Xiangao Huang, Giorgio Inghirami, Maurizio DiLiberto, Selina Chen-Kiang, etc.

Blood. 2019 Mar 14;133(11):1201-1204.

PMID: 30692121

1

Bioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and Humans

Terry Podoll, Paul G Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi, J Greg Slatter

Drug Metab Dispos. 2019 Feb;47(2):145-154.

PMID: 30442651

1

CD21 and FCRL5 Form a Receptor Complex With Robust B-cell Activating Capacity

Andrea Franco, Zachary Kraus, Huifang Li, Naomi Seibert, Jessica Dement-Brown, Mate Tolnay

Int Immunol. 2018 Nov 14;30(12):569-578.

PMID: 30107486

1

From Identification of the BTK Kinase to Effective Management of Leukemia

C I E Smith

Oncogene. 2017 Apr;36(15):2045-2053.

PMID: 27669440

1

The Bruton Tyrosine Kinase Inhibitor PCI-32765 Blocks B-cell Activation and Is Efficacious in Models of Autoimmune Disease and B-cell Malignancy

Lee A Honigberg, Ashley M Smith, Mint Sirisawad, Erik Verner, David Loury, Betty Chang, Shyr Li, Zhengying Pan, Douglas H Thamm, Richard A Miller, Joseph J Buggy

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.

PMID: 20615965

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