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BX-912

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For Research Use Only | Not For Clinical Use
CATAP702674564
CAS702674-56-4
Structure
Molecular Weight471.35
Description≥95% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥95% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Designing New Kinase Inhibitor Derivatives as Therapeutics Against Common Complex Diseases: Structural Basis of Microtubule Affinity-Regulating Kinase 4 (MARK4) Inhibition

Farha Naz, Mohd Shahbaaz, Krishna Bisetty, Asimul Islam, Faizan Ahmad, Md Imtaiyaz Hassan

OMICS. 2015 Nov;19(11):700-11.

PMID: 26565604

1

Evaluation of Human Microtubule Affinity-Regulating Kinase 4 Inhibitors: Fluorescence Binding Studies, Enzyme, and Cell Assays

Farha Naz, Neha Sami, Abu Turab Naqvi, Asimul Islam, Faizan Ahmad, Md Imtaiyaz Hassan

J Biomol Struct Dyn. 2017 Nov;35(14):3194-3203.

PMID: 27748164

1

Novel Small Molecule Inhibitors of 3-phosphoinositide-dependent kinase-1

Richard I Feldman, James M Wu, Mark A Polokoff, Monica J Kochanny, Harald Dinter, Daguang Zhu, Sandra L Biroc, Bruno Alicke, Judi Bryant, Shendong Yuan, Brad O Buckman, Dao Lentz, Mike Ferrer, Marc Whitlow, etc.

J Biol Chem. 2005 May 20;280(20):19867-74.

PMID: 15772071

1

Phosphoinositide-dependent Protein Kinase 1 (PDK1) Mediates Potent Inhibitory Effects on Eosinophils

Eva M Sturm, Gerald P Parzmair, Balázs Radnai, Robert B Frei, Gunter J Sturm, Astrid Hammer, Rufina Schuligoi, Irmgard Th Lippe, Akos Heinemann

Eur J Immunol. 2015 May;45(5):1548-59.

PMID: 25645675

1

Phosphoinositide-dependent Protein Kinase 1 Is a Potential Novel Therapeutic Target in Mantle Cell Lymphoma

Saori Maegawa, Yoshiaki Chinen, Yuji Shimura, Kazuna Tanba, Tomoko Takimoto, Yoshimi Mizuno, Yayoi Matsumura-Kimoto, Saeko Kuwahara-Ota, Taku Tsukamoto, Tsutomu Kobayashi, Shigeo Horiike, Masafumi Taniwaki, etc.

Exp Hematol. 2018 Mar;59:72-81.e2.

PMID: 29287939

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