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C75

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For Research Use Only | Not For Clinical Use
CATAP218137861
CAS218137-86-1
Structure
MDL NumberMFCD03426157
Molecular Weight254.32
InChI KeyVCWLZDVWHQVAJU-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 5 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

An Unexpected Link Between Fatty Acid Synthase and Cholesterol Synthesis in Proinflammatory Macrophage Activation

Richard G Carroll, Zbigniew Zasłona, Silvia Galván-Peña, Emma L Koppe, Daniel C Sévin, Stefano Angiari, Martha Triantafilou, Kathy Triantafilou, Louise K Modis, Luke A O'Neill

J Biol Chem. 2018 Apr 13;293(15):5509-5521.

PMID: 29463677

1

C75 Is Converted to C75-CoA in the Hypothalamus, Where It Inhibits Carnitine Palmitoyltransferase 1 and Decreases Food Intake and Body Weight

Paula Mera, Assia Bentebibel, Eduardo López-Viñas, Antonio G Cordente, Chandrashekaran Gurunathan, David Sebastián, Irene Vázquez, Laura Herrero, Xavier Ariza, Paulino Gómez-Puertas, Guillermina Asins, etc.

Biochem Pharmacol. 2009 Mar 15;77(6):1084-95.

PMID: 19094968

1

Differential Pharmacologic Properties of the Two C75 Enantiomers: (+)-C75 Is a Strong Anorectic Drug; (-)-C75 Has Antitumor Activity

Kamil Makowski, Paula Mera, David Paredes, Laura Herrero, Xavier Ariza, Guillermina Asins, Fausto G Hegardt, Jordi García, Dolors Serra

Chirality. 2013 May;25(5):281-7.

PMID: 23620264

1

Pharmacodynamic Effects of Switching From Ticagrelor to Clopidogrel in Patients With Coronary Artery Disease: Results of the SWAP-4 Study

Francesco Franchi, Fabiana Rollini, Jose Rivas Rios, Andrea Rivas, Malhar Agarwal, Megha Kureti, Deepa Nagaraju, Mustafa Wali, Zubair Shaikh, Maryuri Briceno, Ahmed Nawaz, Jae Youn Moon, Latonya Been, Siva Suryadevara, etc.

Circulation. 2018 Jun 5;137(23):2450-2462.

PMID: 29526833

1

Toll-like Receptor Mediated Inflammation Requires FASN-dependent MYD88 Palmitoylation

Young-Chan Kim, Sang Eun Lee, Somi K Kim, Hyun-Duk Jang, Injoo Hwang, Sooryeonhwa Jin, Eun-Byeol Hong, Kyoung-Soon Jang, Hyo-Soo Kim

Nat Chem Biol. 2019 Sep;15(9):907-916.

PMID: 31427815

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