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CA-074

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For Research Use Only | Not For Clinical Use
CATAP134448105
CAS134448-10-5
Structure
MDL NumberMFCD00797531
Molecular Weight383.44
InChI KeyZEZGJKSEBRELAS-NSIINPIOSA-N
Description≥99% (TLC)
Assay≥99% (TLC)
Size5MG
Storage Conditions−20°C
1

[Cathepsin B in Hepatic Kupffer Cells Regulates Activation of TLR4-independent Inflammatory Pathways in Mice With Lipopolysaccharide-Induced Sepsis]

Panpan Feng, Wei Zhu, Nan Chen, Peizhi Li, Kun He, Jianping Gong

Nan Fang Yi Ke Da Xue Xue Bao. 2018 Dec 30;38(12):1465-1471.

PMID: 30613015

1

CA-074, but Not Its Methyl Ester CA-074Me, Is a Selective Inhibitor of Cathepsin B Within Living Cells

Metwally Montaser, Gilles Lalmanach, Lukas Mach

Biol Chem. Jul-Aug 2002;383(7-8):1305-8.

PMID: 12437121

1

Cathepsin B-independent Abrogation of Cell Death by CA-074-OMe Upstream of Lysosomal Breakdown

R Mihalik, G Imre, I Petak, B Szende, L Kopper

Cell Death Differ. 2004 Dec;11(12):1357-60.

PMID: 15297886

1

Emerging Roles of Microglial Cathepsins in Neurodegenerative Disease

Jessica R Lowry, Andis Klegeris

Brain Res Bull. 2018 May;139:144-156.

PMID: 29454581

1

Inhibitory Effect of Cathepsin B Inhibitor CA 074 on Mouse Anti-Rat Mixed Lymphocyte Reaction: Novel Immunosuppressive Strategy for Indirect Xenoantigen Recognition

T Tohyama, H Kiyochi, K Narumoto, K Honda, N Kobayashi, M Kanoh, T Saibara, N Katunuma

Transplant Proc. 2000 Aug;32(5):944-5.

PMID: 10936287

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