Calphostin C from Cladosporium cladosporioides

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For Research Use Only | Not For Clinical Use

CAT	AP121263192-A
CAS	121263-19-2
Structure
MDL Number	MFCD00133155
Molecular Weight	790.76
InChI Key	SRJYZPCBWDVSGO-UHFFFAOYSA-N

Description	≥90% (HPLC), powder
Solubility	DMF: 1 mg/mL; DMSO: 1 mg/mL; ethanol: 1 mg/mL
Assay	≥90% (HPLC)
Color	red to brown
Form	powder
Size	0.1MG, 1MG
Storage Conditions	−20°C

Calphostin C (UCN-1028C), a Novel Microbial Compound, Is a Highly Potent and Specific Inhibitor of Protein Kinase C

E Kobayashi, H Nakano, M Morimoto, T Tamaoki

Biochem Biophys Res Commun. 1989 Mar 15;159(2):548-53.

PMID: 2467670

Calphostin C Induces Expression of Amphiregulin mRNA via Reactive Oxygen Species in IEC-6 Cells

Y Miyazaki, Y Shinomura, S Tsutsui, S Kitamura, S Hiraoka, Y Matsuzawa

Life Sci. 1998;63(25):PL361-5.

PMID: 9870716

Calphostins (UCN-1028), Novel and Specific Inhibitors of Protein Kinase C. I. Fermentation, Isolation, Physico-Chemical Properties and Biological Activities

E Kobayashi, K Ando, H Nakano, T Iida, H Ohno, M Morimoto, T Tamaoki

J Antibiot (Tokyo). 1989 Oct;42(10):1470-4.

PMID: 2478514

Cladosporium Cladosporioides From the Perspectives of Medical and Biotechnological Approaches

Manaf AlMatar, Essam A Makky

3 Biotech. 2016 Jun;6(1):4.

PMID: 28330073

Inhibition of Protein Kinase C by Calphostin C Is Light-Dependent

R F Bruns, F D Miller, R L Merriman, J J Howbert, W F Heath, E Kobayashi, I Takahashi, T Tamaoki, H Nakano

Biochem Biophys Res Commun. 1991 Apr 15;176(1):288-93.

PMID: 1708246

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