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Carboxyamidotriazole

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For Research Use Only | Not For Clinical Use
CATAP99519843
CAS99519-84-3
Structure
MDL NumberMFCD00866325
Molecular Weight424.67
InChI KeyWNRZHQBJSXRYJK-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL (clear solution)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Carboxyamidotriazole Combined With IDO1-Kyn-AhR Pathway Inhibitors Profoundly Enhances Cancer Immunotherapy

Jing Shi, Chen Chen, Rui Ju, Qingzhu Wang, Juan Li, Lei Guo, Caiying Ye, Dechang Zhang

J Immunother Cancer. 2019 Sep 11;7(1):246.

PMID: 31511064

1

Carboxyamidotriazole Orotate in Glioblastoma

Manjulika Das

Lancet Oncol. 2018 May 3;S1470-2045(18)30347-4.

PMID: 29731337

1

Carboxyamidotriazole-induced Inhibition of Mitochondrial Calcium Import Blocks Capacitative Calcium Entry and Cell Proliferation in HEK-293 Cells

Olivier Mignen, Christine Brink, Antoine Enfissi, Aditi Nadkarni, Trevor J Shuttleworth, David R Giovannucci, Thierry Capiod

J Cell Sci. 2005 Dec 1;118(Pt 23):5615-23.

PMID: 16306224

1

Multicenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas

Antonio Omuro, Kathryn Beal, Katharine McNeill, Robert J Young, Alissa Thomas, Xuling Lin, Robert Terziev, Thomas J Kaley, Lisa M DeAngelis, Mariza Daras, Igor T Gavrilovic, Ingo Mellinghoff, Eli L Diamond, etc.

J Clin Oncol. 2018 Jun 10;36(17):1702-1709.

PMID: 29683790

1

Retraction: Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis

PLOS ONE Editors

PLoS One. 2019 Oct 16;14(10):e0224237.

PMID: 31618259

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