Caspase-1 Inhibitor I, Cell-Permeable - Analytical Products / Alfa Chemistry

CAT	IAR42415323
Molecular Weight	1990.43

Description	The Caspase-1 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.
Solubility	DMSO: 5 mg/mL
Assay	≥97% (HPLC)
Color	white
Form	solid
Size	1MG
Storage Conditions	-20C

1

Cyclophosphamide Induces an Early Wave of Acrolein-Independent Apoptosis in the Urothelium

Francis M Hughes Jr, Alexa G Corn, Andrew R Nimmich, Jeffery D Pratt-Thomas, J Todd Purves

Adv Biosci Biotechnol. 2013 Aug;4(88):10.4236/abb.2013.48A2002.

PMID: 24353901

1

Fused Bicyclic Caspase-1 Inhibitors Assembled by Copper-Free Strain-Promoted Alkyne-Azide Cycloaddition (SPAAC)

Linghui Qian, Chong-Jing Zhang, Ji'en Wu, Shao Q Yao

Chemistry. 2017 Jan 5;23(2):360-369.

PMID: 27882694

1

Inhibition of caspase-1 Induces Cell Death in Pancreatic Carcinoma Cells and Potentially Modulates Expression Levels of bcl-2 Family Proteins

S Schlosser, F Gansauge, M Ramadani, H G Beger, S Gansauge

FEBS Lett. 2001 Feb 23;491(1-2):104-8.

PMID: 11226429

1

Interleukin-1 Mediates endothelin-1-induced Fever and Prostaglandin Production in the Preoptic Area of Rats

Aline S C Fabricio, Giuseppe Tringali, Giacomo Pozzoli, Miriam C Melo, Juliana A Vercesi, Gloria E P Souza, Pierluigi Navarra

Am J Physiol Regul Integr Comp Physiol. 2006 Jun;290(6):R1515-23.

PMID: 16455768

1

Manganese Induces Apoptosis of Human B Cells: Caspase-Dependent Cell Death Blocked by bcl-2

N Schrantz, D A Blanchard, F Mitenne, M T Auffredou, A Vazquez, G Leca

Cell Death Differ. 1999 May;6(5):445-53.

PMID: 10381635