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Caspase Inhibitor

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For Research Use Only | Not For Clinical Use
CATIAR4249310
Molecular Weight538.55
Description≥95% (HPLC)
Assay≥95% (HPLC)
Formlyophilized
Size5MG
Storage Conditions−20°C
1

Application of the Movable Type Free Energy Method to the Caspase-Inhibitor BindingAffinity Study

Song Xue, Hao Liu, Zheng Zheng

Int J Mol Sci. 2019 Sep 29;20(19):4850.

PMID: 31569580

1

Emricasan, a Pan-Caspase Inhibitor, Improves Survival and Portal Hypertension in a Murine Model of Common Bile-Duct Ligation

Akiko Eguchi, Yukinori Koyama, Alexander Wree, Casey D Johnson, Ryota Nakamura, Davide Povero, David Kneiber, Masahiko Tameda, Patricia Contreras, Al Spada, Ariel E Feldstein

J Mol Med (Berl). 2018 Jun;96(6):575-583.

PMID: 29728708

1

The Anti-Caspase Inhibitor Q-VD-OPH Prevents AIDS Disease Progression in SIV-infected Rhesus Macaques

Mireille Laforge, Ricardo Silvestre, Vasco Rodrigues, Julie Garibal, Laure Campillo-Gimenez, Shahul Mouhamad, Valérie Monceaux, Marie-Christine Cumont, Henintsoa Rabezanahary, Alain Pruvost, Anabela Cordeiro-da-Silva, etc.

J Clin Invest. 2018 Apr 2;128(4):1627-1640.

PMID: 29553486

1

The Caspase Inhibitor Z-VAD-FMK Alleviates Endotoxic Shock via Inducing Macrophages Necroptosis and Promoting MDSCs-Mediated Inhibition of Macrophages Activation

Xuehui Li, Xiaoying Yao, Yuzhen Zhu, Hui Zhang, Haiyan Wang, Qun Ma, Fenglian Yan, Yonghong Yang, Junfeng Zhang, Hui Shi, Zhaochen Ning, Jun Dai, Zhihua Li, Chunxia Li, Fei Su, Yin Xue, Xiangzhi Meng, Guanjun Dong, etc.

Front Immunol. 2019 Aug 2;10:1824.

PMID: 31428103

1

The Pan-Caspase Inhibitor Emricasan (IDN-6556) Decreases Liver Injury and Fibrosis in a Murine Model of Non-Alcoholic Steatohepatitis

Fernando J Barreyro, Silvia Holod, Paola V Finocchietto, Alejandra M Camino, Jorge B Aquino, Alejandra Avagnina, María C Carreras, Juan J Poderoso, Gregory J Gores

Liver Int. 2015 Mar;35(3):953-66.

PMID: 24750664

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