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Caspase Inhibitor VI - CAS 161401-82-7

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For Research Use Only | Not For Clinical Use
CATAP161401827
CAS161401-82-7
Molecular Weight453.46
DescriptionZ-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
SolubilityDMSO: 9 mg/mL
Assay≥98% (HPLC)
Coloroff-white
Formsolid; desiccated
Size250μG, 1MG
Storage Conditions-20C
1

Dynamics of caspase-3 Activation and Inhibition in Embryonic Micromasses Evaluated by a Photon-Counting Chemiluminescence Approach

I Chlastakova, M Liskova, J Kudelova, L Dubska, K Kleparnik, E Matalova

In Vitro Cell Dev Biol Anim. 2012 Oct;48(9):545-9.

PMID: 22976371

1

Hepatitis C Virus NS4B Induces the Degradation of TRIF to Inhibit TLR3-mediated Interferon Signaling Pathway

Yisha Liang, Xuezhi Cao, Qiang Ding, Yanan Zhao, Zhenliang He, Jin Zhong

PLoS Pathog. 2018 May 21;14(5):e1007075.

PMID: 29782532

1

Osteogenic Potential of Caspases Related to Endochondral Ossification

Eva Janečková, Petra Bíliková, Eva Matalová

J Histochem Cytochem. 2018 Jan;66(1):47-58.

PMID: 29091523

1

Pharmacological Caspase Inhibitors: Research Towards Therapeutic Perspectives

J Kudelova, J Fleischmannova, E Adamova, E Matalova

J Physiol Pharmacol. 2015 Aug;66(4):473-82.

PMID: 26348072

1

The MEK-ERK-MST1 Axis Potentiates the Activation of the Extrinsic Apoptotic Pathway During GDC-0941 Treatment in Jurkat T Cells

Jana Nováková, Pavel Talacko, Petr Novák, Karel Vališ

Cells. 2019 Feb 21;8(2):191.

PMID: 30795621

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