Cathepsin K Substrate II, Fluorogenic

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For Research Use Only | Not For Clinical Use

CAT	IAR42415992
Molecular Weight	918.91

Description	An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 µM⁻¹ S⁻¹), but not by Cathepsins B/L/S/F/H/V.
Solubility	DMSO: 5 mg/mL
Assay	≥95% (HPLC)
Color	bright yellow
Form	solid; desiccated; protect from light
Size	1MG
Storage Conditions	-20C

Different Cysteine Proteinases Involved in Bone Resorption and Osteoclast Formation

M Brage, M Abrahamson, V Lindström, A Grubb, U H Lerner

Calcif Tissue Int. 2005 Jun;76(6):439-47.

PMID: 15906014

The S2 Subsites of Cathepsins K and L and Their Contribution to Collagen Degradation

Fabien Lecaille, Shafinaz Chowdhury, Enrico Purisima, Dieter Brömme, Gilles Lalmanach

Protein Sci. 2007 Apr;16(4):662-70.

PMID: 17384231

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