Cathepsin S Substrate, Fluorogenic - Analytical Products / Alfa Chemistry

CAT	IAR42415991
Molecular Weight	1991.19

Description	An internally quenched, highly cathepsin S-selective, fluorogenic peptide substrate that is efficiently cleaved by CatS, but not by Cathepsin B & L.
Solubility	DMSO: 5 mg/mL
Assay	≥95% (HPLC)
Color	yellow
Form	solid; desiccated; protect from light
Size	1MG
Storage Conditions	-20C

1

A Bioavailable Cathepsin S Nitrile Inhibitor Abrogates Tumor Development

Richard D A Wilkinson, Andrew Young, Roberta E Burden, Rich Williams, Christopher J Scott

Mol Cancer. 2016 Apr 21;15:29.

PMID: 27097645

1

Cathepsin D From Alzheimer's-diseased and Normal Brains

R E Kohnken, U S Ladror, G T Wang, T F Holzman, B E Miller, G A Krafft

Exp Neurol. 1995 Jun;133(2):105-12.

PMID: 7649217

1

Cathepsin S Cannibalism of Cathepsin K as a Mechanism to Reduce Type I Collagen Degradation

Zachary T Barry, Manu O Platt

J Biol Chem. 2012 Aug 10;287(33):27723-30.

PMID: 22730330

1

Fluorogenic Peptide Substrates for Carboxydipeptidase Activity of Cathepsin B

Krystyna Stachowiak, Monika Tokmina, Anna Karpińska, Renata Sosnowska, Wiesław Wiczk

Acta Biochim Pol. 2004;51(1):81-92.

PMID: 15094828

1

Synthesis and Hydrolysis by Cathepsin B of Fluorogenic Substrates With the General Structure benzoyl-X-ARG-MCA Containing Non-Natural Basic Amino Acids at Position X

R L Melo, R C Barbosa Pozzo, L C Alves, E Perissutti, G Caliendo, V Santagada, L Juliano, M A Juliano

Biochim Biophys Acta. 2001 May 5;1547(1):82-94.

PMID: 11343794

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