CAS 21919-05-1 CB 1954 - Analytical Products / Alfa Chemistry

CAT	AP21919051
CAS	21919-05-1
Structure
MDL Number	MFCD00869490
InChI Key	WOCXQMCIOTUMJV-UHFFFAOYSA-N

1

CB 1954 (2,4-dinitro-5-aziridinyl Benzamide) Becomes a DNA Interstrand Crosslinking Agent in Walker Tumour Cells

J J Roberts, F Friedlos, R J Knox

Biochem Biophys Res Commun. 1986 Nov 14;140(3):1073-8.

PMID: 3778483

1

CB 1954: From the Walker Tumor to NQO2 and VDEPT

Richard J Knox, Philip J Burke, Shiuan Chen, David J Kerr

Curr Pharm Des. 2003;9(26):2091-104.

PMID: 14529407

1

Combinatorial Effects of Thymoquinone on the Anticancer Activity and Hepatotoxicity of the Prodrug CB 1954

Wamidh H Talib, Majed M Abukhader

Sci Pharm. Apr-Jun 2013;81(2):519-30.

PMID: 23833717

1

Demonstration of the Activation of Prodrug CB 1954 Using Human DT-diaphorase Mutant Q104Y-transfected MDA-MB-231 Cells and Mouse Xenograft Model

K Wu, E Eng, R Knox, S Chen

Arch Biochem Biophys. 2001 Jan 1;385(1):203-8.

PMID: 11361019

1

The Bioactivation of CB 1954 and Its Use as a Prodrug in Antibody-Directed Enzyme Prodrug Therapy (ADEPT)

R J Knox, F Friedlos, M P Boland

Cancer Metastasis Rev. 1993 Jun;12(2):195-212.

PMID: 8375021