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CCG-50014

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For Research Use Only | Not For Clinical Use

CAT	AP883050246
CAS	883050-24-6
Structure
Molecular Weight	316.35

Description	≥98% (HPLC)
Solubility	DMSO: 5 mg/mL, clear (warmed)
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1

A Nanomolar-Potency Small Molecule Inhibitor of Regulator of G-protein Signaling Proteins

Levi L Blazer, Haoming Zhang, Emma M Casey, Stephen M Husbands, Richard R Neubig

Biochemistry. 2011 Apr 19;50(15):3181-92.

PMID: 21329361

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1

An Interhelical Salt Bridge Controls Flexibility and Inhibitor Potency for Regulators of G-protein Signaling Proteins 4, 8, and 19

Vincent S Shaw, Mohammadjavad Mohammadi, Josiah A Quinn, Harish Vashisth, Richard R Neubig

Mol Pharmacol. 2019 Dec;96(6):683-691.

PMID: 31543506

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1

Conformational Dynamics of a Regulator of G-protein Signaling Protein Reveals a Mechanism of Allosteric Inhibition by a Small Molecule

Harish Vashisth, Andrew J Storaska, Richard R Neubig, Charles L Brooks 3rd

ACS Chem Biol. 2013 Dec 20;8(12):2778-84.

PMID: 24093330

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