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CD111/Nectin-1/PVRL1 human

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For Research Use Only | Not For Clinical Use
CATIAR42413177
Descriptionrecombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Assay≥95% (SDS-PAGE)
Formlyophilized; observed mol wt 45-60 kDa (DTT-reduced. Protein migrates due to glycosylation. Gln 31 is the predicted N-terminus.); pkg of 50 μg
Impurity Content<1 EU/μg endotoxin (LAL test)
Size10UG, 50UG
Storage Conditions−20°C
1

Engineered Herpes Simplex Viruses Efficiently Infect and Kill CD133+ Human Glioma Xenograft Cells That Express CD111

Gregory K Friedman, Catherine P Langford, Jennifer M Coleman, Kevin A Cassady, Jacqueline N Parker, James M Markert, G Yancey Gillespie

J Neurooncol. 2009 Nov;95(2):199-209.

PMID: 19521665

1

Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates With Nectin-1 Expression

Gregory K Friedman, Joshua D Bernstock, Dongquan Chen, Li Nan, Blake P Moore, Virginia M Kelly, Samantha L Youngblood, Catherine P Langford, Xiaosi Han, Eric K Ring, Elizabeth A Beierle, G Yancey Gillespie, etc.

Sci Rep. 2018 Sep 17;8(1):13930.

PMID: 30224769

1

Functional Characterization of Human CD34+ Cells That Express Low or High Levels of the Membrane Antigen CD111 (Nectin 1)

G Belaaloui, A-M Imbert, F Bardin, C Tonnelle, P Dubreuil, M Lopez, C Chabannon

Leukemia. 2003 Jun;17(6):1137-45.

PMID: 12764381

1

Preclinical Evaluation of Engineered Oncolytic Herpes Simplex Virus for the Treatment of Pediatric Solid Tumors

Michael L Megison, Lauren A Gillory, Jerry E Stewart, Hugh C Nabers, Elizabeth Mroczek-Musulman, Alicia M Waters, Jennifer M Coleman, Virginia Kelly, James M Markert, G Yancey Gillespie, Gregory K Friedman, etc.

PLoS One. 2014 Jan 30;9(1):e86843.

PMID: 24497984

1

Role for Plasmacytoid Dendritic Cells in the Immune Control of Recurrent Human Herpes Simplex Virus Infection

Heather Donaghy, Lidija Bosnjak, Andrew N Harman, Valerie Marsden, Stephen K Tyring, Tze-Chiang Meng, Anthony L Cunningham

J Virol. 2009 Feb;83(4):1952-61.

PMID: 19073735

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