CD47 human - Analytical Products / Alfa Chemistry

CAT

IAR42413182

Description	recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Assay	≥95% (SDS-PAGE)
Form	lyophilized; observed mol wt 35-43 kDa (DTT-reduced. Protein migrates due to glycosylation. Gln 19 is the predicted N-terminus.)
Impurity Content	<1 EU/μg endotoxin (LAL test)
Size	10UG
Storage Conditions	−20°C

1

Anti-leukemic Activity and Tolerability of Anti-Human CD47 Monoclonal Antibodies

E C Pietsch, J Dong, R Cardoso, X Zhang, D Chin, R Hawkins, T Dinh, M Zhou, B Strake, P-H Feng, M Rocca, C Dos Santos, X Shan, G Danet-Desnoyers, F Shi, E Kaiser, H J Millar, S Fenton, R Swanson, J A Nemeth, etc.

Blood Cancer J. 2017 Feb 24;7(2):e536.

PMID: 28234345

1

Cancer Immunotherapy Targeting the CD47/SIRPα Axis

Kipp Weiskopf

Eur J Cancer. 2017 May;76:100-109.

PMID: 28286286

1

CD47 Is a Novel Potent Immunotherapy Target in Human Malignancies: Current Studies and Future Promises

Bing Tong, Mengzhao Wang

Future Oncol. 2018 Sep;14(21):2179-2188.

PMID: 29667847

1

Targeting CD47 as a Cancer Therapeutic Strategy: The Cutaneous T-cell Lymphoma Experience

Alecia S Folkes, Mingye Feng, Jasmine M Zain, Farah Abdulla, Steven T Rosen, Christiane Querfeld

Curr Opin Oncol. 2018 Sep;30(5):332-337.

PMID: 29994903

1

The CD47-signal Regulatory Protein Alpha (SIRPa) Interaction Is a Therapeutic Target for Human Solid Tumors

Stephen B Willingham, Jens-Peter Volkmer, Andrew J Gentles, Debashis Sahoo, Piero Dalerba, Siddhartha S Mitra, Jian Wang, Humberto Contreras-Trujillo, Robin Martin, Justin D Cohen, Patricia Lovelace, Ferenc A Scheeren, etc.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6662-7.

PMID: 22451913

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