CD58/LFA-3 human

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For Research Use Only | Not For Clinical Use

CAT

IAR42413191

Description	recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Assay	≥95% (SDS-PAGE)
Form	lyophilized; observed mol wt 30-45 kDa (DTT-reduced. Protein migrates due to glycosylation. Phe 29 is the predicted N-terminal.); pkg of 50 μg
Size	10UG, 50UG
Storage Conditions	−20°C

CD58 (LFA-3) Stimulation Provides a Signal for Human Isotype Switching and IgE Production Distinct From CD40

D Diaz-Sanchez, S Chegini, K Zhang, A Saxon

J Immunol. 1994 Jul 1;153(1):10-20.

PMID: 7515920

Human Cell-Adhesion Molecule CD2 Binds CD58 (LFA-3) With a Very Low Affinity and an Extremely Fast Dissociation Rate but Does Not Bind CD48 or CD59

P A van der Merwe, A N Barclay, D W Mason, E A Davies, B P Morgan, M Tone, A K Krishnam, C Ianelli, S J Davis

Biochemistry. 1994 Aug 23;33(33):10149-60.

PMID: 7520278

Immunomodulatory Properties of Soluble Recombinant Human CD58 (LFA-3) Molecules

M Albert-Wolf, S C Meuer, R Wallich

Dev Biol Stand. 1992;77:87-92.

PMID: 1385237

MHC Class II Ligation Induces CD58 (LFA-3)-mediated Adhesion in Human T Cells

M Nielsen, J Gerwien, C Geisler, C Röpke, A Svejgaard, N Odum

Exp Clin Immunogenet. 1998;15(2):61-8.

PMID: 9691200

The CD58 (LFA-3) Binding Site Is a Localized and Highly Charged Surface Area on the AGFCC'C" Face of the Human CD2 Adhesion Domain

A R Arulanandam, J M Withka, D F Wyss, G Wagner, A Kister, P Pallai, M A Recny, E L Reinherz

Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11613-7.

PMID: 7505442

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