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Celgosivir

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For Research Use Only | Not For Clinical Use
CATAP121104969
CAS121104-96-9
Structure
MDL NumberMFCD00886617
Molecular Weight259.30
Description≥98% (HPLC)
SolubilityH2O: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder; under inert gas
Size5MG, 25MG
Storage Conditions−20°C
1

Antiviral Screening of Multiple Compounds Against Ebola Virus

Stuart D Dowall, Kevin Bewley, Robert J Watson, Seshadri S Vasan, Chandradhish Ghosh, Mohini M Konai, Gro Gausdal, James B Lorens, Jason Long, Wendy Barclay, Isabel Garcia-Dorival, Julian Hiscox, Andrew Bosworth, etc.

Viruses. 2016 Oct 27;8(11):277.

PMID: 27801778

1

Celgosivir Treatment Misfolds Dengue Virus NS1 Protein, Induces Cellular Pro-Survival Genes and Protects Against Lethal Challenge Mouse Model

Abhay P S Rathore, Prasad N Paradkar, Satoru Watanabe, Kah Hin Tan, Cynthia Sung, John E Connolly, Jenny Low, Eng Eong Ooi, Subhash G Vasudevan

Antiviral Res. 2011 Dec;92(3):453-60.

PMID: 22020302

1

Celgosivir, an Alpha-Glucosidase I Inhibitor for the Potential Treatment of HCV Infection

David Durantel

Curr Opin Investig Drugs. 2009 Aug;10(8):860-70.

PMID: 19649930

1

Dose- And Schedule-Dependent Protective Efficacy of Celgosivir in a Lethal Mouse Model for Dengue Virus Infection Informs Dosing Regimen for a Proof of Concept Clinical Trial

Satoru Watanabe, Abhay P S Rathore, Cynthia Sung, Fan Lu, Yok Moi Khoo, John Connolly, Jenny Low, Eng Eong Ooi, How Sung Lee, Subhash G Vasudevan

Antiviral Res. 2012 Oct;96(1):32-5.

PMID: 22867971

1

Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

Cynthia Sung, Yuan Wei, Satoru Watanabe, How Sung Lee, Yok Moi Khoo, Lu Fan, Abhay P S Rathore, Kitti Wing-Ki Chan, Milly M Choy, Uma S Kamaraj, October M Sessions, Pauline Aw, Paola F de Sessions, Bernett Lee, etc.

PLoS Negl Trop Dis. 2016 Aug 10;10(8):e0004851.

PMID: 27509020

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