CAS 307510-92-5 CFTR(inh)-172 - Analytical Products / Alfa Chemistry

CAT	AP307510925
CAS	307510-92-5
MDL Number	MFCD06411408
Molecular Weight	409.40
InChI Key	JIMHYXZZCWVCMI-RIYZIHGNSA-N

Description	≥98% (HPLC), powder
Solubility	DMSO: ≥10 mg/mL; H2O: insoluble
Assay	≥98% (HPLC)
Color	yellow
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1

cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity

Chung-Ming Tse, Jianyi Yin, Varsha Singh, Rafiquel Sarker, Ruxian Lin, Alan S Verkman, Jerrold R Turner, Mark Donowitz

Cell Mol Gastroenterol Hepatol. 2019;7(3):641-653.

PMID: 30659943

1

Cystic Fibrosis Transmembrane Conductance Regulator Modulates Enteric Cholinergic Activities and Is Abnormally Expressed in the Enteric Ganglia of Patients With Slow Transit Constipation

Ka Ming Yeh, Olle Johansson, Huy Le, Karan Rao, Irit Markus, Dayashan Shevy Perera, David Zachary Lubowski, Denis Warwick King, Li Zhang, Hongzhuan Chen, Lu Liu

J Gastroenterol. 2019 Nov;54(11):994-1006.

PMID: 31392489

1

Cystic Fibrosis Transmembrane Regulator Inhibitors CFTR(inh)-172 and GlyH-101 Target Mitochondrial Functions, Independently of Chloride Channel Inhibition

Mairead Kelly, Stephanie Trudel, Franck Brouillard, Frederick Bouillaud, Julien Colas, Thao Nguyen-Khoa, Mario Ollero, Aleksander Edelman, Janine Fritsch

J Pharmacol Exp Ther. 2010 Apr;333(1):60-9.

PMID: 20051483

1

Divergent CFTR Orthologs Respond Differently to the Channel Inhibitors CFTRinh-172, Glibenclamide, and GlyH-101

Maximilian Stahl, Klaus Stahl, Marie B Brubacher, John N Forrest Jr

Am J Physiol Cell Physiol. 2012 Jan 1;302(1):C67-76.

PMID: 21940661

1

Evidence for Direct CFTR Inhibition by CFTR(inh)-172 Based on Arg347 Mutagenesis

Emanuela Caci, Antonella Caputo, Alexandre Hinzpeter, Nicole Arous, Pascale Fanen, Nitin Sonawane, A S Verkman, Roberto Ravazzolo, Olga Zegarra-Moran, Luis J V Galietta

Biochem J. 2008 Jul 1;413(1):135-42.

PMID: 18366345

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