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CGP77675

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For Research Use Only | Not For Clinical Use
CATAP234772646
CAS234772-64-6
MDL NumberMFCD20039929
Molecular Weight443.54
InChI KeyWUPXZZWTHIZICK-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: >10 mg/mL
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

[The Role of Src-kinase in the Regulation of Endocytosis of EGF-receptor Complexes. I. Dynamics of EGF Internalization, Recycling, Sorting, and Degradation During Inhibition of Src-kinase Activity]

N N Zheleznova, M S Melikova, N N Nikol'skiĭ, E S Kornilova

Tsitologiia. 2001;43(12):1136-45.

PMID: 11881152

1

A Novel Inhibitor of the Tyrosine Kinase Src Suppresses Phosphorylation of Its Major Cellular Substrates and Reduces Bone Resorption in Vitro and in Rodent Models in Vivo

M Missbach, M Jeschke, J Feyen, K Müller, M Glatt, J Green, M Susa

Bone. 1999 May;24(5):437-49.

PMID: 10321903

1

Inhibition of Protein Kinase c-Src as a Therapeutic Approach for Cancer and Bone Metastases

Nadia Rucci, Maria Susa, Anna Teti

Anticancer Agents Med Chem. 2008 Apr;8(3):342-9.

PMID: 18393792

1

Inhibition of Src Kinases Combined With CD40 Ligand Blockade Prolongs Murine Cardiac Allograft Survival

Qiwei Zhang, Robert L Fairchild, Martha B Reich, Geraldine G Miller

Transplantation. 2005 Oct 27;80(8):1112-20.

PMID: 16278594

1

Synthesis, Biological Evaluation and Docking Studies of New pyrrolo[2,3-d] Pyrimidine Derivatives as Src Family-Selective Tyrosine Kinase Inhibitors

Sebla Dincer, Kadir Taylan Cetin, Arzu Onay-Besikci, Süreyya Ölgen

J Enzyme Inhib Med Chem. 2013 Oct;28(5):1080-7.

PMID: 22957720

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