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Chromanol 293B

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For Research Use Only | Not For Clinical Use
CATAP163163233
CAS163163-23-3
Structure
MDL NumberMFCD06798368
Molecular Weight324.40
InChI KeyHVSJHHXUORMCGK-UONOGXRCSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 18 mg/mL
Assay≥98% (HPLC)
Colorwhite
Formpowder
Size10MG, 50MG
Storage Conditions−20°C
1

Characterization of Chromanol 293B-induced Block of the Delayed-Rectifier K+ Current in Heart-Derived H9c2 Cells

Yi-Ching Lo, Su-Rong Yang, Mei-Han Huang, Yen-Chin Liu, Sheng-Nan Wu

Life Sci. 2005 Apr 1;76(20):2275-86.

PMID: 15748622

1

Chromanol 293B Binding in KCNQ1 (Kv7.1) Channels Involves Electrostatic Interactions With a Potassium Ion in the Selectivity Filter

Christian Lerche, Iva Bruhova, Holger Lerche, Klaus Steinmeyer, Aguan D Wei, Nathalie Strutz-Seebohm, Florian Lang, Andreas E Busch, Boris S Zhorov, Guiscard Seebohm

Mol Pharmacol. 2007 Jun;71(6):1503-11.

PMID: 17347319

1

Chromanol 293B Inhibits Slowly Activating Delayed Rectifier and Transient Outward Currents in Canine Left Ventricular Myocytes

Z Q Sun, G P Thomas, C Antzelevitch

J Cardiovasc Electrophysiol. 2001 Apr;12(4):472-8.

PMID: 11332571

1

Chromanol 293B, a Blocker of the Slow Delayed Rectifier K+ Current (IKs), Inhibits the CFTR Cl- Current

A Bachmann, U Quast, U Russ

Naunyn Schmiedebergs Arch Pharmacol. 2001 Jun;363(6):590-6.

PMID: 11414653

1

Chromanol 293B, an Inhibitor of KCNQ1 Channels, Enhances Glucose-Stimulated Insulin Secretion and Increases Glucagon-Like peptide-1 Level in Mice

Lijie Liu, Fanfan Wang, Haiying Lu, Xiaomei Ren, Jihong Zou

Islets. 2014;6(4):e962386.

PMID: 25437377

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