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Chromomycin A3 from Streptomyces griseus

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For Research Use Only | Not For Clinical Use
CATAP7059247
CAS7059-24-7
Structure
MDL NumberMFCD00043151
Molecular Weight1183.25
EC Number230-348-0
InChI KeyZYVSOIYQKUDENJ-MTPXVABGSA-N
Description≥95% (HPLC)
Assay≥95% (HPLC); fungi; neoplastics
Size5MG, 10MG
Storage Conditions−20°C
1

Biosynthesis of the Antitumor Chromomycin A3 in Streptomyces Griseus: Analysis of the Gene Cluster and Rational Design of Novel Chromomycin Analogs

Nuria Menéndez, Mohammad Nur-e-Alam, Alfredo F Braña, Jürgen Rohr, José A Salas, Carmen Méndez

Chem Biol. 2004 Jan;11(1):21-32.

PMID: 15112992

1

Characterization of the Terminal Activation Step Catalyzed by Oxygenase CmmOIV of the Chromomycin Biosynthetic Pathway From Streptomyces Griseus

Mary A Bosserman, Ana B Flórez, Khaled A Shaaban, Alfredo F Braña, Jose A Salas, Carmen Méndez, Jürgen Rohr

Biochemistry. 2011 Mar 1;50(8):1421-8.

PMID: 21244022

1

Deoxysugar Transfer During Chromomycin A3 Biosynthesis in Streptomyces Griseus Subsp. Griseus: New Derivatives With Antitumor Activity

Nuria Menéndez, Mohammad Nur-e-Alam, Carsten Fischer, Alfredo F Braña, José A Salas, Jürgen Rohr, Carmen Méndez

Appl Environ Microbiol. 2006 Jan;72(1):167-77.

PMID: 16391039

1

Involvement of a Chromomycin ABC Transporter System in Secretion of a Deacetylated Precursor During Chromomycin Biosynthesis

Nuria Menéndez, Alfredo F Braña, José A Salas, Carmen Méndez

Microbiology. 2007 Sep;153(Pt 9):3061-3070.

PMID: 17768249

1

Tailoring Modification of Deoxysugars During Biosynthesis of the Antitumour Drug Chromomycin A by Streptomyces Griseus Ssp. Griseus

Nuria Menéndez, Mohammad Nur-E-Alam, Alfredo F Braña, Jürgen Rohr, José A Salas, Carmen Méndez

Mol Microbiol. 2004 Aug;53(3):903-15.

PMID: 15255901

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