CAS 289499-45-2 CI-1033 - Analytical Products / Alfa Chemistry

CAT	AP289499452
CAS	289499-45-2
Structure
MDL Number	MFCD09954112
Molecular Weight	558.86
InChI Key	JZZFDCXSFTVOJY-UHFFFAOYSA-N

Description	≥98% (HPLC)
Solubility	DMSO: >10 mg/mL; H2O: >10 mg/mL
Assay	≥98% (HPLC)
Form	solid
Size	5MG, 25MG
Storage Conditions	−20°C

1

Administration of CI-1033, an Irreversible pan-erbB Tyrosine Kinase Inhibitor, Is Feasible on a 7-day On, 7-day Off Schedule: A Phase I Pharmacokinetic and Food Effect Study

Emiliano Calvo, Anthony W Tolcher, Lisa A Hammond, Amita Patnaik, Johan S de Bono, Irene A Eiseman, Stephen C Olson, Peter F Lenehan, Heather McCreery, Patricia Lorusso, Eric K Rowinsky

Clin Cancer Res. 2004 Nov 1;10(21):7112-20.

PMID: 15534081

1

CI-1033, a pan-erbB Tyrosine Kinase Inhibitor

W J Slichenmyer, W L Elliott, D W Fry

Semin Oncol. 2001 Oct;28(5 Suppl 16):80-5.

PMID: 11706399

1

Induction of Apoptosis by Ionizing Radiation and CI-1033 in HuCCT-1 Cells

Masateru Murakami, Tamito Sasaki, Souichirou Yamasaki, Kenichi Kuwahara, Hideki Miyata, Kazuaki Chayama

Biochem Biophys Res Commun. 2004 Jun 18;319(1):114-9.

PMID: 15158449

1

Radiosensitization by Pan ErbB Inhibitor CI-1033 in Vitro and in Vivo

Mukesh K Nyati, Divya Maheshwari, Sheela Hanasoge, Arun Sreekumar, Susan D Rynkiewicz, Arul M Chinnaiyan, Wilbur R Leopold, Stephen P Ethier, Theodore S Lawrence

Clin Cancer Res. 2004 Jan 15;10(2):691-700.

PMID: 14760092

1

The pan-erbB Tyrosine Kinase Inhibitor CI-1033 Inhibits Human Esophageal Cancer Cells in Vitro and in Vivo

E Ako, Y Yamashita, M Ohira, M Yamazaki, T Hori, N Kubo, T Sawada, K Hirakawa

Oncol Rep. 2007 Apr;17(4):887-93.

PMID: 17342332

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