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CI 976

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For Research Use Only | Not For Clinical Use
CATAP114289473
CAS114289-47-3
Structure
MDL NumberMFCD00869662
Molecular Weight393.56
InChI KeyWAFNZAURAWBNDZ-UHFFFAOYSA-N
Description>98% (HPLC), solid
SolubilityDMSO: >10 mg/mL; H2O: insoluble <2 mg/mL
Assay>98% (HPLC)
Formsolid
Size5MG
Storage Conditions2-8°C
1

A Lysophospholipid Acyltransferase Antagonist, CI-976, Creates Novel Membrane Tubules Marked by Intracellular Phospholipase A1 KIAA0725p

Takashi Baba, Akitsugu Yamamoto, Mitsuo Tagaya, Katsuko Tani

Mol Cell Biochem. 2013 Apr;376(1-2):151-61.

PMID: 23378048

1

A Unique Lysophospholipid Acyltransferase (LPAT) Antagonist, CI-976, Affects Secretory and Endocytic Membrane Trafficking Pathways

Kimberly Chambers, Bret Judson, William J Brown

J Cell Sci. 2005 Jul 15;118(Pt 14):3061-71.

PMID: 15972316

1

Characterization of a Novel CI-976-sensitive Lysophospholipid Acyltransferase That Is Associated With the Golgi Complex

Kimberly Chambers, William J Brown

Biochem Biophys Res Commun. 2004 Jan 16;313(3):681-6.

PMID: 14697244

1

Comparison of CI-976, an ACAT Inhibitor, and Selected Lipid-Lowering Agents for Antiatherosclerotic Activity in Iliac-Femoral and Thoracic Aortic Lesions. A Biochemical, Morphological, and Morphometric Evaluation

T M Bocan, S B Mueller, P D Uhlendorf, R S Newton, B R Krause

Arterioscler Thromb. Nov-Dec 1991;11(6):1830-43.

PMID: 1931885

1

In Vivo Evidence That the Lipid-Regulating Activity of the ACAT Inhibitor CI-976 in Rats Is Due to Inhibition of Both Intestinal and Liver ACAT

B R Krause, M Anderson, C L Bisgaier, T Bocan, R Bousley, P DeHart, A Essenburg, K Hamelehle, R Homan, K Kieft

J Lipid Res. 1993 Feb;34(2):279-94.

PMID: 8429262

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