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CIL-102

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For Research Use Only | Not For Clinical Use
CATAP479077764
CAS479077-76-4
Structure
MDL NumberMFCD08277043
Molecular Weight302.33
InChI KeyVJDPGTFIMDGXDQ-UHFFFAOYSA-N
Description≥95% (HPLC), solid
SolubilityDMSO: 12 mg/mL
Assay≥95% (HPLC)
Formsolid
Size10MG
Storage Conditions−20°C
1

CIL-102 Binds to Tubulin at Colchicine Binding Site and Triggers Apoptosis in MCF-7 Cells by Inducing Monopolar and Multinucleated Cells

K K Gireesh, Aijaz Rashid, Soumyananda Chakraborti, Dulal Panda, Tapas Manna

Biochem Pharmacol. 2012 Sep 1;84(5):633-45.

PMID: 22705644

1

CIL-102 Induces Matrix metalloproteinase-2 (MMP-2)/MMP-9 Down-Regulation via Simultaneous Suppression of Genetic Transcription and mRNA Stability

Wen-Hsin Liu, Yeh-Long Chen, Long-Sen Chang

Int J Biochem Cell Biol. 2012 Dec;44(12):2212-22.

PMID: 22964005

1

CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45

Wen-Shih Huang, Yi-Hung Kuo, Hsing-Chun Kuo, Meng-Chiao Hsieh, Cheng-Yi Huang, Ko-Chao Lee, Kam-Fai Lee, Chien-Heng Shen, Shui-Yi Tung, Chih-Chuan Teng

PLoS One. 2017 Jan 9;12(1):e0168989.

PMID: 28068431

1

Novel CIL-102 Derivatives as Potential Therapeutic Agents for Docetaxel-Resistant Prostate Cancer

Dannah R Miller, Cherng-Chyi Tzeng, Trey Farmer, Evan T Keller, Steve Caplan, Yu-Shuin Chen, Yeh-Long Chen, Ming-Fong Lin

Cancer Lett. 2018 Nov 1;436:96-108.

PMID: 30077739

1

The Inhibitory Effect of CIL-102 on the Growth of Human Astrocytoma Cells Is Mediated by the Generation of Reactive Oxygen Species and Induction of ERK1/2 MAPK

Chih-Chuan Teng, Hsing-Chun Kuo, Ho-Chen Cheng, Ting-Chung Wang, Chun-I Sze

Toxicol Appl Pharmacol. 2012 Aug 15;263(1):73-80.

PMID: 22683510

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