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cis-Diamminetetrachloroplatinum(IV)

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For Research Use Only | Not For Clinical Use
CATAP16893053
CAS16893-05-3
Structure
MDL NumberMFCD00050045
Molecular Weight370.95
EC Number240-930-6
InChI KeyRBHOYUZKIANPPG-UHFFFAOYSA-J
Description99.9% trace metals basis
Assay99.9% trace metals basis
Formpowder
Linear FormulaPt(NH3)2Cl4
MP>300 °C (lit.)
Size1G
1

Detection of DNA Strand Breaks in Escherichia Coli Treated With platinum(IV) Antitumor Compounds

M Defais, M Germanier, N P Johnson

Chem Biol Interact. 1990;74(3):343-52.

PMID: 2112045

1

Induction and Repair of DNA Cross-Links in Chinese Hamster Ovary Cells Treated With Various Platinum Coordination Compounds in Relation to Platinum Binding to DNA, Cytotoxicity, Mutagenicity, and Antitumor Activity

A C Plooy, M van Dijk, P H Lohman

Cancer Res. 1984 May;44(5):2043-51.

PMID: 6538808

1

Platinum(II) Catalysis and Radical Intervention in Reductions of platinum(IV) Antitumor Drugs by Ascorbic Acid

Evelyne L Weaver, Rathindra N Bose

J Inorg Biochem. 2003 Jul 1;95(4):231-9.

PMID: 12818793

1

Reduction of Ormaplatin and Cis-Diamminetetrachloroplatinum(iv) by Ascorbic Acid and Dominant Thiols in Human Plasma: Kinetic and Mechanistic Analyses

Jingran Dong, Yanli Ren, Shuying Huo, Shigang Shen, Jianzhong Xu, Hongwu Tian, Tiesheng Shi

Dalton Trans. 2016 Jul 28;45(28):11326-37.

PMID: 27327648

1

Toxicity, Mutagenicity and Induction of recA Protein in Escherichia Coli Treated With cis-diamminedichloroplatinum(II) and cis-diamminetetrachloroplatinum(IV)

H Razaka, B Salles, G Villani, N P Johnson

Chem Biol Interact. 1986 Nov;60(2):207-15.

PMID: 3539376

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