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Cisplatin

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For Research Use Only | Not For Clinical Use
CATAP15663271-A
CAS15663-27-1
Structure
MDL NumberMFCD00011623
Molecular Weight300.05
EC Number239-733-8
InChI KeyLXZZYRPGZAFOLE-UHFFFAOYSA-L
DescriptionPharmaceutical Secondary Standard; Certified Reference Material
Gradecertified reference material; pharmaceutical secondary standard
Linear FormulaPt(NH3)2Cl2
MP270 °C (lit.); traceable to USP 1134357
Size200MG
1

CDK2 Inhibitors as Candidate Therapeutics for Cisplatin- And Noise-Induced Hearing Loss

Tal Teitz, Jie Fang, Asli N Goktug, Justine D Bonga, Shiyong Diao, Robert A Hazlitt, Luigi Iconaru, Marie Morfouace, Duane Currier, Yinmei Zhou, Robyn A Umans, Michael R Taylor, Cheng Cheng, Jaeki Min, etc.

J Exp Med. 2018 Apr 2;215(4):1187-1203.

PMID: 29514916

1

Cisplatin Is Retained in the Cochlea Indefinitely Following Chemotherapy

Andrew M Breglio, Aaron E Rusheen, Eric D Shide, Katharine A Fernandez, Katie K Spielbauer, Katherine M McLachlin, Matthew D Hall, Lauren Amable, Lisa L Cunningham

Nat Commun. 2017 Nov 21;8(1):1654.

PMID: 29162831

1

Cisplatin-Induced Ototoxicity: Updates on Molecular Targets

Erica Gentilin, Edi Simoni, Mariarita Candito, Diego Cazzador, Laura Astolfi

Trends Mol Med. 2019 Dec;25(12):1123-1132.

PMID: 31473143

1

Mechanisms of Cisplatin-Induced Ototoxicity and Prevention

Leonard P Rybak, Debashree Mukherjea, Vickram Ramkumar

Semin Hear. 2019 May;40(2):197-204.

PMID: 31036996

1

Molecular Mechanisms of Cisplatin Resistance

L Galluzzi, L Senovilla, I Vitale, J Michels, I Martins, O Kepp, M Castedo, G Kroemer

Oncogene. 2012 Apr 12;31(15):1869-83.

PMID: 21892204

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