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Clostridium difficile Toxin B

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For Research Use Only | Not For Clinical Use
CATIAR4242912
MDL NumberMFCD02098002
Description≥95% (SDS-PAGE)
Assay≥95% (SDS-PAGE)
Formlyophilized powder
Size2UG, 50UG
Storage Conditions2-8°C
1

Clostridium Difficile Toxin B Induces Senescence in Enteric Glial Cells: A Potential New Mechanism of Clostridium Difficile Pathogenesis

Katia Fettucciari, Lara Macchioni, Magdalena Davidescu, Paolo Scarpelli, Camilla Palumbo, Lanfranco Corazzi, Andrea Marchegiani, Matteo Cerquetella, Andrea Spaterna, Pierfrancesco Marconi, Gabrio Bassotti

Biochim Biophys Acta Mol Cell Res. 2018 Dec;1865(12):1945-1958.

PMID: 30296499

1

Frizzled Proteins Are Colonic Epithelial Receptors for C. Difficile Toxin B

Liang Tao, Jie Zhang, Paul Meraner, Alessio Tovaglieri, Xiaoqian Wu, Ralf Gerhard, Xinjun Zhang, William B Stallcup, Ji Miao, Xi He, Julian G Hurdle, David T Breault, Abraham L Brass, Min Dong

Nature. 2016 Oct 20;538(7625):350-355.

PMID: 27680706

1

Neutralization of Clostridium Difficile Toxin B With VHH-Fc Fusions Targeting the Delivery and CROPs Domains

Greg Hussack, Shannon Ryan, Henk van Faassen, Martin Rossotti, C Roger MacKenzie, Jamshid Tanha

PLoS One. 2018 Dec 12;13(12):e0208978.

PMID: 30540857

1

Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B

Peng Chen, Liang Tao, Tianyu Wang, Jie Zhang, Aina He, Kwok-Ho Lam, Zheng Liu, Xi He, Kay Perry, Min Dong, Rongsheng Jin

Science. 2018 May 11;360(6389):664-669.

PMID: 29748286

1

Structure of the Full-Length Clostridium Difficile Toxin B

Peng Chen, Kwok-Ho Lam, Zheng Liu, Frank A Mindlin, Baohua Chen, Craig B Gutierrez, Lan Huang, Yongrong Zhang, Therwa Hamza, Hanping Feng, Tsutomu Matsui, Mark E Bowen, Kay Perry, Rongsheng Jin

Nat Struct Mol Biol. 2019 Aug;26(8):712-719.

PMID: 31308519

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