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CMPPE

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For Research Use Only | Not For Clinical Use
CATAP841253814
CAS841253-81-4
Structure
MDL NumberMFCD05710220
Molecular Weight370.88
InChI KeyTZWSGOPCLUTFBZ-UHFFFAOYSA-N
Description≥95% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥95% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Anticonvulsant Effects of Structurally Diverse GABA(B) Positive Allosteric Modulators in the DBA/2J Audiogenic Seizure Test: Comparison to Baclofen and Utility as a Pharmacodynamic Screening Model

Jordan W Brown, Achim Moeller, Martin Schmidt, Sean C Turner, Volker Nimmrich, Junli Ma, Lynne E Rueter, Elizabeth van der Kam, Min Zhang

Neuropharmacology. 2016 Feb;101:358-69.

PMID: 26471422

1

Efficacy and Side Effects of Baclofen and the Novel GABA

Valentina Vengeliene, Tatiane T Takahashi, Olga A Dravolina, Irina Belozertseva, Edwin Zvartau, Anton Y Bespalov, Rainer Spanagel

Psychopharmacology (Berl). 2018 Jul;235(7):1955-1965.

PMID: 29651507

1

In Vitro and in Vivo Characterization of the Novel GABAB Receptor Positive Allosteric Modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE)

Elisabetta Perdona', Vivian J A Costantini, Michela Tessari, Prisca Martinelli, Corrado Carignani, Enzo Valerio, M H Selina Mok, Laura Zonzini, Filippo Visentini, Massimo Gianotti, Laurie Gordon, Magalie Rocheville, etc.

Neuropharmacology. Oct-Nov 2011;61(5-6):957-66.

PMID: 21756923

1

Suppressing Effect of CMPPE, a New Positive Allosteric Modulator of the GABA

Paola Maccioni, Federica Fara, Irene Lorrai, Carla Acciaro, Claudia Mugnaini, Federico Corelli, Giancarlo Colombo

Alcohol. 2019 Mar;75:79-87.

PMID: 30468987

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