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CP-74416 methanesulfonate hydrate

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For Research Use Only | Not For Clinical Use
CATALP108461047
CAS108461-04-7 (free base)
Molecular Weight439.46 (anhydrous basis)
Description≥98% (HPLC)
SolubilityH2O: ≥22 mg/mL
Assay≥98% (HPLC)
Colorwhite to tan
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Discriminative-stimulus Effects of the Low Efficacy Mu Agonist Nalbuphine

E A Walker, A M Young

J Pharmacol Exp Ther. 1993 Oct;267(1):322-30.

PMID: 8229759

1

Kappa Agonists Inhibit Gastric Emptying but Not Acid Secretion in Rhesus Monkeys

P L Touzeau, T Shea-Donohue

J Pharmacol Exp Ther. 1990 Jun;253(3):1010-6.

PMID: 1972746

1

Production of Hypothermia in the Guinea Pig by a Kappa-Agonist Opioid Alone and in Combination With Chlorpromazine

M W Adler, E Bradley, R Martinez, E B Geller

Pharmacol Biochem Behav. 1991 Sep;40(1):129-32.

PMID: 1664107

1

Spinal G-protein-gated Potassium Channels Contribute in a Dose-Dependent Manner to the Analgesic Effect of Mu- And Delta- But Not Kappa-Opioids

Cheryl L Marker, Rafael Luján, Horace H Loh, Kevin Wickman

J Neurosci. 2005 Apr 6;25(14):3551-9.

PMID: 15814785

1

Targeting Group II Metabotropic Glutamate (mGlu) Receptors for the Treatment of Psychosis Associated With Alzheimer's Disease: Selective Activation of mGlu2 Receptors Amplifies Beta-Amyloid Toxicity in Cultured Neurons, Whereas Dual Activation of mGlu2 and mGlu3 Receptors Is Neuroprotective

Filippo Caraci, Gemma Molinaro, Giuseppe Battaglia, Maria Laura Giuffrida, Barbara Riozzi, Anna Traficante, Valeria Bruno, Milena Cannella, Sara Merlo, Xushan Wang, Beverly A Heinz, Eric S Nisenbaum, Thomas C Britton, etc.

Mol Pharmacol. 2011 Mar;79(3):618-26.

PMID: 21159998

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