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CP-96345

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For Research Use Only | Not For Clinical Use
CATAP132746602
CAS132746-60-2
MDL NumberMFCD00900615
Molecular Weight412.57
InChI KeyFLNYLINBEZROPL-NSOVKSMOSA-N
Description≥98% (HPLC)
SolubilityDMSO: 24 mg/mL
Assay≥98% (HPLC)
Formwhite powder
Size5MG, 25MG
Storage Conditionsroom temp
1

Amino-aromatic Interaction Between Histidine 197 of the neurokinin-1 Receptor and CP 96345

T M Fong, M A Cascieri, H Yu, A Bansal, C Swain, C D Strader

Nature. 1993 Mar 25;362(6418):350-3.

PMID: 8384323

1

Blockade of Tachykinin NK1 Receptors by CP-96345 Enhances Dopamine Release and the Striatal Dopamine Effects of Methamphetamine in Rats

S P Gygi, J W Gibb, M Johnson, G R Hanson

Eur J Pharmacol. 1993 Nov 30;250(1):177-80.

PMID: 7509751

1

Differences in the Potency of CP-96345 and RP-67580, Two New Non-Peptide Antagonists Selective for NK1 Receptors, in Inhibiting Responses Evoked by Stimulation of Sensory Nerves

P Delay-Goyet, H Satoh, P Stjärne, J Rinder, J M Lundberg

Regul Pept. 1993 Jul 2;46(1-2):304-6.

PMID: 7692522

1

Substance P and IL-33 Administered Together Stimulate a Marked Secretion of IL-1β From Human Mast Cells, Inhibited by Methoxyluteolin

Alexandra Taracanova, Irene Tsilioni, Pio Conti, Errol R Norwitz, Susan E Leeman, Theoharis C Theoharides

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9381-E9390.

PMID: 30232261

1

Substance P Antagonist CP-96345 Blocks Lung Vascular Leakage and Inflammation More Effectively Than Its Stereoisomer CP-96344 in a Mouse Model of Smoke Inhalation and Burn Injury

Sam Jacob, Donald J Deyo, Robert A Cox, Reuben K Jacob, David N Herndon, Daniel L Traber, Hal K Hawkins

Toxicol Mech Methods. 2010 May;20(4):197-203.

PMID: 20201741

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