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CPCCOEt

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For Research Use Only | Not For Clinical Use
CATAP179067993
CAS179067-99-3
Structure
MDL NumberMFCD00947859
Molecular Weight247.25
InChI KeyFXCTZFMSAHZQTR-KAMYIIQDSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

CPCCOEt, a Noncompetitive Metabotropic Glutamate Receptor 1 Antagonist, Inhibits Receptor Signaling Without Affecting Glutamate Binding

S Litschig, F Gasparini, D Rueegg, N Stoehr, P J Flor, I Vranesic, L Prézeau, J P Pin, C Thomsen, R Kuhn

Mol Pharmacol. 1999 Mar;55(3):453-61.

PMID: 10051528

1

Discovery and Characterization of Non-Competitive Antagonists of Group I Metabotropic Glutamate Receptors

F Gasparini, P Floersheim, P J Flor, M Heinrich, W Inderbitzin, D Ott, A Pagano, C Stierlin, N Stoehr, I Vranesic, R Kuhn

Farmaco. Jan-Feb 2001;56(1-2):95-9.

PMID: 11347975

1

Interaction of CPCCOEt With a Chimeric mGlu1b and Calcium Sensing Receptor

H Bräuner-Osborne, A A Jensen, P Krogsgaard-Larsen

Neuroreport. 1999 Dec 16;10(18):3923-5.

PMID: 10716234

1

The mGlu1 Antagonist CPCCOEt Enhances the Climbing Fibre Response in Purkinje Neurones Independently of Glutamate Receptors

Izumi Fukunaga, Christopher H Yeo, Andrew M Batchelor

Neuropharmacology. 2007 Feb;52(2):450-8.

PMID: 17045308

1

The Non-Competitive Metabotropic Glutamate receptor-1 Antagonist CPCCOEt Inhibits the in Vitro Growth of Human Melanoma

Helga Susanne Haas, Roswitha Pfragner, Veronika Siegl, Elisabeth Ingolic, Elfgard Heintz, Elisabeth Schraml, Konrad Schauenstein

Oncol Rep. 2007 Jun;17(6):1399-404.

PMID: 17487397

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