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CPI203

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For Research Use Only | Not For Clinical Use
CATAP1446144042
CAS1446144-04-2
MDL NumberMFCD27997886
Molecular Weight399.90
InChI KeyQECMENZMDBOLDR-AWEZNQCLSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Pharmacological Modulation of CXCR4 Cooperates With BET Bromodomain Inhibition in Diffuse Large B-cell Lymphoma

Clara Recasens-Zorzo, Teresa Cardesa-Salzmann, Paolo Petazzi, Laia Ros-Blanco, Anna Esteve-Arenys, Guillem Clot, Martina Guerrero-Hernández, Vanina Rodríguez, Davide Soldini, Alexandra Valera, Alexandra Moros, etc.

Haematologica. 2019 Apr;104(4):778-788.

PMID: 29954928

1

The BET Bromodomain Inhibitor CPI203 Improves Lenalidomide and Dexamethasone Activity in

Tania Díaz, Vanina Rodríguez, Ester Lozano, Mari-Pau Mena, Marcos Calderón, Laura Rosiñol, Antonio Martínez, Natalia Tovar, Patricia Pérez-Galán, Joan Bladé, Gaël Roué, Carlos Fernández de Larrea

Haematologica. 2017 Oct;102(10):1776-1784.

PMID: 28751557

1

The BET Bromodomain Inhibitor CPI203 Overcomes Resistance to ABT-199 (Venetoclax) by Downregulation of BFL-1/A1 in in Vitro and in Vivo Models of MYC+/BCL2+ Double Hit Lymphoma

A Esteve-Arenys, J G Valero, A Chamorro-Jorganes, D Gonzalez, V Rodriguez, I Dlouhy, I Salaverria, E Campo, D Colomer, A Martinez, G Rymkiewicz, P Pérez-Galán, A Lopez-Guillermo, G Roué

Oncogene. 2018 Apr;37(14):1830-1844.

PMID: 29353886

1

Vitamin C Sensitizes Melanoma to BET Inhibitors

Sushmita Mustafi, Vladimir Camarena, Claude-Henry Volmar, Tyler C Huff, David W Sant, Shaun P Brothers, Zhao-Jun Liu, Claes Wahlestedt, Gaofeng Wang

Cancer Res. 2018 Jan 15;78(2):572-583.

PMID: 29180474

1

Vitamin C Supplementation Expands the Therapeutic Window of BETi for Triple Negative Breast Cancer

Sushmita Mustafi, Vladimir Camarena, Rehana Qureshi, Hyunho Yoon, Claude-Henry Volmar, Tyler C Huff, David W Sant, Lihong Zheng, Shaun P Brothers, Claes Wahlestedt, Joyce Slingerland, Gaofeng Wang

EBioMedicine. 2019 May;43:201-210.

PMID: 30975544

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